KEGG   ENZYME: 2.3.1.66Help
Entry
EC 2.3.1.66                 Enzyme                                 

Name
leucine N-acetyltransferase;
leucine acetyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acetyl-CoA:L-leucine N-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + L-leucine = CoA + N-acetyl-L-leucine [RN:R01089]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
L-leucine [CPD:C00123]
Product
CoA [CPD:C00010];
N-acetyl-L-leucine [CPD:C02710]
Comment
Propanoyl-CoA can act as a donor, but more slowly. L-Arginine, L-valine, L-phenylalanine and peptides containing L-leucine can act as acceptors.
History
EC 2.3.1.66 created 1983
Reference
1
  Authors
Suzukake, S., Hayashi, H., Hori, M. and Umezawa, H.
  Title
Biosnthesis of leupeptin III. Isolation and properties of an enzyme synthesizing acetyl-L-leucine.
  Journal
J. Antibiot. 33 (1982) 857-862.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
75496-56-9

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