KEGG   ENZYME: 2.3.1.67Help
Entry
EC 2.3.1.67                 Enzyme                                 
Name
1-alkylglycerophosphocholine O-acetyltransferase;
acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase;
acetyl-CoA:lyso-PAF acetyltransferase;
1-alkyl-2-lysolecithin acetyltransferase;
acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase;
blood platelet-activating factor acetyltransferase;
lyso-GPC:acetyl CoA acetyltransferase;
lyso-platelet activating factor:acetyl-CoA acetyltransferase;
lysoPAF:acetyl CoA acetyltransferase;
PAF acetyltransferase;
platelet-activating factor acylhydrolase;
platelet-activating factor-synthesizing enzyme;
1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase;
lyso-platelet-activating factor:acetyl-CoA acetyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine = CoA + 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine [RN:R03437]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
1-alkyl-sn-glycero-3-phosphocholine [CPD:C04317]
Product
CoA [CPD:C00010];
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine [CPD:C04598]
Pathway
Ether lipid metabolism
Metabolic pathways
Orthology
K13510  
lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase
Genes
HSA: 
54947(LPCAT2) 79888(LPCAT1)
PTR: 
454095(LPCAT2) 461698(LPCAT1)
PPS: 
100970278(LPCAT2) 100991866(LPCAT1)
GGO: 
PON: 
100435855(LPCAT1) 100449928(LPCAT2)
MCC: 
698605(LPCAT2) 710144(LPCAT1)
MMU: 
210992(Lpcat1) 270084(Lpcat2)
RNO: 
100359680(Lpcat2) 361467(Lpcat1)
CFA: 
488066(LPCAT1) 611330(LPCAT2)
AML: 
FCA: 
101095078(LPCAT1) 101099093(LPCAT2)
BTA: 
514646(LPCAT2) 788450(LPCAT1)
SSC: 
100217397(LPCAT1) 100517894(LPCAT2)
ECB: 
100061308(LPCAT2) 100071898
MDO: 
100014768(LPCAT2) 100015539
SHR: 
100915216(LPCAT1) 100935270(LPCAT2)
OAA: 
100074850 100077162(LPCAT2)
GGA: 
415716(LPCAT2) 420974(LPCAT1)
MGP: 
100546916 100547104
TGU: 
100218938(LPCAT2) 100224379(LPCAT1)
ACS: 
100557762(lpcat2) 100563014
XTR: 
100124943(lpcat2) 100487143
DRE: 
553683(lpcat2) 555969(lpcat1)
TRU: 
101067621 101078533
OLA: 
101159130 101172965
BFO: 
BRAFLDRAFT_222039
CIN: 
100181981
SPU: 
579107
DME: 
Dmel_CG32699
DPO: 
Dpse_GA23062
DAN: 
Dana_GF22630
DER: 
Dere_GG18969
DPE: 
Dper_GL13112
DSE: 
Dsec_GM11357
DSI: 
Dsim_GD16057
DWI: 
Dwil_GK10139
DYA: 
Dyak_GE15443
DGR: 
Dgri_GH12406
DMO: 
Dmoj_GI15857
DVI: 
Dvir_GJ19019
AGA: 
AgaP_AGAP000596
AAG: 
AaeL_AAEL001448
CQU: 
CpipJ_CPIJ010179
AME: 
550970
NVI: 
100120270(NV17021)
TCA: 
657636
PHU: 
Phum_PHUM293230
TSP: 
Tsp_09580
SMM: 
Smp_132850.1
NVE: 
NEMVE_v1g160653
HMG: 
100203846
TAD: 
TRIADDRAFT_63570
ATH: 
AT1G80950 AT2G45670
ALY: 
ARALYDRAFT_477149 ARALYDRAFT_483703
GMX: 
100775331 100818109 100820536
MTR: 
MTR_7g104580
CSV: 
101209255 101218421 101223404
RCU: 
RCOM_1593790 RCOM_1612980
POP: 
POPTR_1098087 POPTR_551926 POPTR_591825 POPTR_851914
VVI: 
100262557 100267860
OSA: 
4338527 4342043
DOSA: 
Os05t0357800-01(Os05g0357800) Os06t0712300-01(Os06g0712300)
BDI: 
100832624 100834306 100836765
SBI: 
SORBI_03g012600(SORBIDRAFT_03g012600) SORBI_10g029780(SORBIDRAFT_10g029780)
ZMA: 
100191712(TIDP3349) 100193648(cl15598_1c) 100284702
SMO: 
SELMODRAFT_121336 SELMODRAFT_123670 SELMODRAFT_150199 SELMODRAFT_184257 SELMODRAFT_420881 SELMODRAFT_65256
PPP: 
PHYPADRAFT_163873 PHYPADRAFT_201778 PHYPADRAFT_213782 PHYPADRAFT_43926
CRE: 
CHLREDRAFT_189038
VCN: 
VOLCADRAFT_73089 VOLCADRAFT_91941
CME: 
CMS008C
MBR: 
MONBRDRAFT_33064
PTM: 
GSPATT00003417001
GLA: 
GL50803_15987
PIF: 
PITG_18374
 » show all
Taxonomy
Reference
1  [PMID:7430122]
  Authors
Wykle RL, Malone B, Snyder F.
  Title
Enzymatic synthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine, a hypotensive and platelet-aggregating lipid.
  Journal
J. Biol. Chem. 255 (1980) 10256-60.
  Organism
Bos taurus [GN:bta]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
76773-96-1
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