KEGG   ENZYME: 2.3.1.73Help
Entry
EC 2.3.1.73                 Enzyme                                 

Name
diacylglycerol---sterol O-acyltransferase;
1,2-diacyl-sn-glycerol:sterol acyl transferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
1,2-diacyl-sn-glycerol:sterol O-acyltransferase
Reaction(IUBMB)
a 1,2-diacyl-sn-glycerol + sterol = a 1-acyl-sn-glycerol + sterol ester [RN:R02693]
Reaction(KEGG)
Substrate
1,2-diacyl-sn-glycerol [CPD:C00641];
sterol [CPD:C00370]
Product
1-acyl-sn-glycerol;
sterol ester [CPD:C01958]
Comment
Cholesterol, sitosterol, campesterol and diacylglycerol can act as acceptors. Transfers a number of long-chain fatty acyl groups.
History
EC 2.3.1.73 created 1984
Pathway
Steroid biosynthesis
Reference
1
  Authors
Bartlett, K., Keat, M.J. and Mercer, E.I.
  Title
Biosynthesis of sterol esters in Phycomyces blakesleeanus.
  Journal
Phytochemistry 13 (1974) 1107-1113.
Reference
2  [PMID:742884]
  Authors
Garcia RE, Mudd JB.
  Title
Metabolism of monoacylglycerol and diacylglycerol by enzyme preparations from spinach leaves.
  Journal
Arch. Biochem. Biophys. 191 (1978) 487-93.
Reference
3
  Authors
Garcia, R.E. and Mudd, J.B.
  Title
1,2-Diacyl-sn-glycerol:sterol acyl transferase from spinach leaves (Spinacia oleracea L.).
  Journal
Methods Enzymol. 71 (1981) 768-772.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
79586-23-5

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