KEGG   ENZYME: 2.3.1.75Help
Entry
EC 2.3.1.75                 Enzyme                                 

Name
long-chain-alcohol O-fatty-acyltransferase;
wax synthase;
wax-ester synthase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:long-chain-alcohol O-acyltransferase
Reaction(IUBMB)
acyl-CoA + a long-chain alcohol = CoA + a long-chain ester [RN:R01999]
Reaction(KEGG)
Substrate
acyl-CoA [CPD:C00040];
long-chain alcohol [CPD:C00339]
Product
CoA [CPD:C00010];
long-chain ester [CPD:C02434]
Comment
Transfers saturated or unsaturated acyl residues of chain-length C18 to C20 to long-chain alcohols, forming waxes. The best acceptor is cis-icos-11-en-1-ol.
History
EC 2.3.1.75 created 1984
Pathway
Cutin, suberine and wax biosynthesis
Orthology
K11155  
diacylglycerol O-acyltransferase 1
K11156  
diacylglycerol O-acyltransferase 2-like protein 4
K11160  
diacylglycerol O-acyltransferase 2
K11171  
diacylglycerol O-acyltransferase 2-like protein 3
K15406  
wax-ester synthase / diacylglycerol O-acyltransferase
Genes
HSA: 
158833(AWAT1) 158835(AWAT2) 84649(DGAT2) 8694(DGAT1)
PTR: 
464460(DGAT1) 465684(AWAT1) 466714(DGAT2) 473654(AWAT2)
PPS: 
100969745(AWAT2) 100972494(AWAT1) 100987880(DGAT2) 100994391(DGAT1)
GGO: 
101124495(AWAT1) 101124779(DGAT2) 101142898(DGAT1) 101153985(AWAT2)
PON: 
100442216(DGAT2) 100444717(AWAT2) 100448768(AWAT1) 100453587(DGAT1)
MCC: 
695011(AWAT1) 696451(AWAT2) 696549 701489(DGAT1)
MCF: 
102121566(DGAT1) 102128601(DGAT2) 102128700(AWAT2) 102130614(AWAT1)
MMU: 
13350(Dgat1) 245532(Awat2) 245533(Awat1) 67800(Dgat2)
RNO: 
252900(Dgat2) 302425(Awat2) 679520(Awat1) 84497(Dgat1)
CGE: 
100755985(Dgat1) 100768365(Awat2) 100769131(Awat1) 100774981(Dgat2)
HGL: 
101698712(Dgat2) 101701856(Awat2) 101703747(Awat1) 101723650(Dgat1) 101728676
TUP: 
102474487(DGAT1) 102484046(AWAT1) 102494423(DGAT2) 102502982(AWAT2)
CFA: 
482093(DGAT1) 485185(DGAT2) 491936(AWAT2) 491938(AWAT1)
AML: 
FCA: 
101086879(AWAT2) 101087643(AWAT1) 101100329(DGAT2) 101101615(DGAT1)
PTG: 
102952153(DGAT2) 102952284(DGAT1) 102971579(AWAT1) 102972443(AWAT2)
BTA: 
282609(DGAT1) 404129(DGAT2) 521298(AWAT2) 529893(AWAT1)
BOM: 
102270405(AWAT1) 102275983(AWAT2) 102277779(DGAT1) 102285649(DGAT2)
PHD: 
CHX: 
100861225(DGAT1) 102174409(DGAT2) 102175661(AWAT1) 102177144(AWAT2)
OAS: 
100126245(DGAT1) 101110535(DGAT2) 101121241(AWAT2) 101122414(AWAT1)
SSC: 
100151799(AWAT2) 100294675(DGAT2) 100517507(AWAT1) 397118(DGAT)
CFR: 
102504113(DGAT2) 102514200(AWAT2) 102514959(AWAT1) 102515256(DGAT1)
BACU: 
103001320(DGAT1) 103009724(AWAT2) 103018277(DGAT2)
LVE: 
103073062(DGAT1) 103074572(AWAT2) 103075069(DGAT2)
ECB: 
100056316(AWAT1) 100064387(DGAT2) 100066473(AWAT2) 100147359(DGAT1)
MYB: 
102242085(AWAT2) 102249216 102261774(DGAT2) 102263477(AWAT1) 102263903(DGAT1)
MYD: 
102751521(AWAT1) 102753473(DGAT2) 102760049(AWAT2) 102769363(DGAT1)
PALE: 
102885568(AWAT1) 102889573(DGAT1) 102895732(AWAT2) 102898739(DGAT2)
MDO: 
100011089(DGAT2) 100014237(AWAT1) 100014456(AWAT2) 100018271(DGAT1)
SHR: 
100914285(DGAT2) 100924635 100931966(AWAT2) 100933522(AWAT1)
OAA: 
100088895(DGAT2)
GGA: 
421309(DGAT2) 428693
TGU: 
100220095(DGAT2)
FAB: 
PHI: 
APLA: 
101801215(DGAT2)
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
103052621(DGAT2) 103065772(DGAT1)
XLA: 
398800(dgat2)
XTR: 
100127752(dgat2l6) 101730812(dgat1) 395003(dgat2)
DRE: 
325875(dgat1a) 565316(dgat2)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
552377(mdy)
NVI: 
TCA: 
BMOR: 
PHU: 
ISC: 
CEL: 
CBR: 
BMY: 
LOA: 
TSP: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
ATH: 
AT2G19450(TAG1) AT5G37300(WSD1)
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
547982(DGAT) 548005(DAGAT1) 732606(DGAT1b)
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os05t0196800-00(Os05g0196800) Os06t0563900-01(Os06g0563900)
OBR: 
BDI: 
SBI: 
SORBI_09g006110(SORBIDRAFT_09g006110) SORBI_10g022270(SORBIDRAFT_10g022270)
ZMA: 
SITA: 
ATR: 
s00036p00158260(AMTR_s00036p00158260)
SMO: 
PPP: 
VCN: 
CSL: 
CVR: 
CME: 
GSL: 
CCP: 
YLI: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_1456054(AO090011000863)
ANG: 
ANI_1_1688104(An12g03600)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
ECU: 
EIN: 
EHE: 
NCE: 
MBR: 
DDI: 
DPP: 
DFA: 
ACAN: 
TET: 
PTI: 
TPS: 
EHX: 
GTT: 
NGR: 
 » show all
Taxonomy
Reference
1
  Authors
Wu, X.-Y., Moreau, R.A. and Stumpf, P.K.
  Title
Studies of biosynthesis of waxes by developing jojoba seed. 3. Biosynthesis of wax esters from acyl-CoA and long-chain alcohols.
  Journal
Lipids 16 (1981) 897-902.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
64060-40-8

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