KEGG   ENZYME: 2.3.3.12Help
Entry
EC 2.3.3.12                 Enzyme                                 

Name
3-propylmalate synthase;
3-(n-propyl)-malate synthase;
3-propylmalate glyoxylate-lyase (CoA-pentanoylating);
beta-n-propylmalate synthase;
n-propylmalate synthase
Class
Transferases;
Acyltransferases;
Acyl groups converted into alkyl groups on transfer
BRITE hierarchy
Sysname
pentanoyl-CoA:glyoxylate C-pentanoyltransferase (thioester-hydrolysing, 1-carboxybutyl-forming)
Reaction(IUBMB)
pentanoyl-CoA + H2O + glyoxylate = 3-propylmalate + CoA [RN:R03040]
Reaction(KEGG)
Substrate
pentanoyl-CoA [CPD:C00888];
H2O [CPD:C00001];
glyoxylate [CPD:C00048]
Product
3-propylmalate [CPD:C02123];
CoA [CPD:C00010]
History
EC 2.3.3.12 created 1972 as EC 4.1.3.11, transferred 2002 to EC 2.3.3.12
Pathway
Glyoxylate and dicarboxylate metabolism
Reference
1  [PMID:14085361]
  Authors
IMAI K, REEVES HC, AJL SJ.
  Title
N-PROPYLMALATE SYNTHETASE.
  Journal
J. Biol. Chem. 238 (1963) 3193-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37290-62-3

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