KEGG   ENZYME: 2.4.1.197Help
Entry
EC 2.4.1.197                Enzyme                                 

Name
high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase;
uridine diphosphoacetylglucosamine-oligosaccharide acetylglucosaminyltransferase;
acetylglucosamine-oligosaccharide acetylglucosaminyltransferase;
UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase;
UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide 4-beta-N-acetylglucosaminyltransferase
Reaction(IUBMB)
Transfers an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-(1->6) to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum
Comment
The activity of the intersecting mannose residue as acceptor is dependent on two other mannose residues attached by alpha-1,3 and alpha-1,6 links.
History
EC 2.4.1.197 created 1992
Reference
1  [PMID:2525124]
  Authors
Sharkey DJ, Kornfeld R.
  Title
Identification of an N-acetylglucosaminyltransferase in Dictyostelium discoideum that transfers an "intersecting" N-acetylglucosamine residue to high mannose oligosaccharides.
  Journal
J. Biol. Chem. 264 (1989) 10411-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
123425-54-7

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