KEGG   ENZYME: 2.4.1.219Help
Entry
EC 2.4.1.219                Enzyme                                 

Name
vomilenine glucosyltransferase;
UDPG:vomilenine 21-beta-D-glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-glucose:vomilenine 21-O-beta-D-glucosyltransferase
Reaction(IUBMB)
UDP-glucose + vomilenine = UDP + raucaffricine [RN:R05882]
Reaction(KEGG)
Substrate
UDP-glucose [CPD:C00029];
vomilenine [CPD:C01761]
Product
UDP [CPD:C00015];
raucaffricine [CPD:C02074]
Comment
The indole alkaloid raucaffricine accumulates during the culture of Rauvolfia cell suspensions.
History
EC 2.4.1.219 created 2002
Pathway
Indole alkaloid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K12695  
raucaffricine beta-D-glucosidase / vomilenine glucosyltransferase
Reference
1  [PMID:10234858]
  Authors
Warzecha H, Obitz P, Stockigt J.
  Title
Purification, partial amino acid sequence and structure of the product of raucaffricine-O-beta-D-glucosidase from plant cell cultures of Rauwolfia serpentina.
  Journal
Phytochemistry. 50 (1999) 1099-109.
Reference
2  [PMID:10975500]
  Authors
Warzecha H, Gerasimenko I, Kutchan TM, Stockigt J.
  Title
Molecular cloning and functional bacterial expression of a plant glucosidase specifically involved in alkaloid biosynthesis.
  Journal
Phytochemistry. 54 (2000) 657-66.
  Sequence
Reference
3
  Authors
Ruyter, C.M. and Stockigt, J.
  Title
Enzymatic formation of raucaffricine, the major indole alkaloid of Rauwolfia serpentina cell-suspension cultures.
  Journal
Helv. Chim. Acta 74 (1991) 1707-1712.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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