KEGG   ENZYME: 2.4.1.254Help
Entry
EC 2.4.1.254                Enzyme                                 

Name
cyanidin-3-O-glucoside 2''-O-glucuronosyltransferase;
BpUGT94B1;
UDP-glucuronic acid:anthocyanin glucuronosyltransferase;
UDP-glucuronic acid:anthocyanidin 3-glucoside 2'-O-beta-glucuronosyltransferase;
BpUGAT;
UDP-D-glucuronate:cyanidin-3-O-beta-glucoside 2-O-beta-glucuronosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-glucuronate:cyanidin-3-O-beta-D-glucoside 2-O-beta-D-glucuronosyltransferase
Reaction(IUBMB)
UDP-alpha-D-glucuronate + cyanidin 3-O-beta-D-glucoside = UDP + cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside [RN:R09635]
Reaction(KEGG)
R09635;
(other) R07932
Show
Substrate
UDP-alpha-D-glucuronate [CPD:C00167];
cyanidin 3-O-beta-D-glucoside [CPD:C08604]
Product
UDP [CPD:C00015];
cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside [CPD:C19762]
Comment
The enzyme is highly specific for cyanidin 3-O-glucosides and UDP-alpha-D-glucuronate. Involved in the production of glucuronosylated anthocyanins that are the origin of the red coloration of flowers of Bellis perennis [1].
History
EC 2.4.1.254 created 2011
Pathway
Anthocyanin biosynthesis
Orthology
K12937  
cyanidin-3-O-glucoside 2''-O-glucuronosyltransferase
Genes
CIC: 
EGR: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
VVI: 
SLY: 
SOT: 
 » show all
Taxonomy
Reference
1  [PMID:15509561]
  Authors
Sawada S, Suzuki H, Ichimaida F, Yamaguchi MA, Iwashita T, Fukui Y, Hemmi H, Nishino T, Nakayama T
  Title
UDP-glucuronic acid:anthocyanin glucuronosyltransferase from red daisy (Bellis perennis) flowers. Enzymology and phylogenetics of a novel glucuronosyltransferase involved in flower pigment biosynthesis.
  Journal
J. Biol. Chem. 280 (2005) 899-906.
  Sequence
Reference
2  [PMID:18829982]
  Authors
Osmani SA, Bak S, Imberty A, Olsen CE, Moller BL
  Title
Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses.
  Journal
Plant. Physiol. 148 (2008) 1295-308.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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