KEGG   ENZYME: 2.4.1.291Help
Entry
EC 2.4.1.291                Enzyme                                 

Name
N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase;
PglJ
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-N-acetyl-alpha-D-galactosamine:N-acetylgalactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol 3-alpha-N-acetyl-D-galactosaminyltransferase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol = UDP + N-acetyl-D-galactosaminyl-alpha-(1->4)-N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Substrate
UDP-N-acetyl-alpha-D-galactosamine [CPD:C00203];
N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Product
UDP [CPD:C00015];
N-acetyl-D-galactosaminyl-alpha-(1->4)-N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Comment
Isolated from Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway.
History
EC 2.4.1.291 created 2012
Orthology
K17248  N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase
Genes
PUL: NT08PM_0024
VDB: AL552_09575
PEA: PESP_a0485
AMAL: I607_07515
AMAE: I876_07775
AMAO: I634_07890
AMAC: MASE_07390
AMB: AMBAS45_07910
AMG: AMEC673_07440
AMK: AMBLS11_07390
CJE: Cj1127c(pglJ)
CJB: BN148_1127c(pglJ)
CJJ: CJJ81176_1144(pglJ)
CJU: C8J_1067(pglJ)
CJI: CJSA_1069(pglJ)
CJM: CJM1_1105(pglJ)
CJS: CJS3_1173(pglJ)
CJEJ: N564_01095
CJEU: N565_01138
CJEN: N755_01131
CJEI: N135_01164
CJER: H730_06605
CJV: MTVDSCj20_1130(pglJ)
CJY: QZ67_01205(pglJ)
CJQ: UC78_1084(pglJ)
CJR: CJE1269(pglJ)
CJD: JJD26997_0594(pglJ)
CFX: CFV97608_1522(pglJ)
CCV: CCV52592_1214(pglJ)
CCO: CCC13826_0453(pglJ)
CCOC: CCON33237_1466(pglJ)
CLA: Cla_1252(pglJ)
CLR: UPTC16701_1235(pglJ)
CLM: UPTC16712_1253(pglJ)
CLQ: UPTC4110_1237(pglJ)
CLN: UPTC3659_1472(pglJ)
CLL: CONCH_1203(pglJ)
CCQ: N149_1068
CCF: YSQ_03335
CCY: YSS_06100
CCOI: YSU_03370
CCOF: VC76_05530(pglJ)
CCOO: ATE51_01350(pglJ)
CIS: CINS_1217(pglJ)
CVO: CVOL_1231(pglJ)
CPEL: CPEL_1358(pglJ)
CAMR: CAQ16704_1263(pglJ)
CSM: CSUB8521_1439(pglJ)
CSF: CSUB8523_1535(pglJ)
CGRA: CGRAC_1491(pglJ)
CURE: CUREO_1375(pglJ)
CHYO: CHH_0376(pglJ)
CHV: CHELV3228_0553(pglJ)
CSPF: CSF_0894(pglJ)
CPIN: CPIN18020_0861(pglJ)
CCUN: CCUN_1170(pglJ)
CLX: CLAN_0353(pglJ)
SHAL: SHALO_2917
FIN: KQS_09110
RAG: B739_1131
 » show all
Taxonomy
Reference
1  [PMID:16186480]
  Authors
Glover KJ, Weerapana E, Imperiali B
  Title
In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 14255-9.
  Sequence
[cje:Cj1127c]
Reference
2  [PMID:18034500]
  Authors
Chen MM, Weerapana E, Ciepichal E, Stupak J, Reid CW, Swiezewska E, Imperiali B
  Title
Polyisoprenol specificity in the Campylobacter jejuni N-linked glycosylation pathway.
  Journal
Biochemistry. 46 (2007) 14342-8.
  Sequence
[cje:Cj1127c]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.291
IUBMB Enzyme Nomenclature: 2.4.1.291
ExPASy - ENZYME nomenclature database: 2.4.1.291
BRENDA, the Enzyme Database: 2.4.1.291

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