KEGG   ENZYME: 2.4.1.291Help
Entry
EC 2.4.1.291                Enzyme                                 

Name
N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase;
PglJ
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-N-acetyl-alpha-D-galactosamine:N-acetylgalactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol 3-alpha-N-acetyl-D-galactosaminyltransferase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol = UDP + N-acetyl-D-galactosaminyl-alpha-(1->4)-N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Substrate
UDP-N-acetyl-alpha-D-galactosamine [CPD:C00203];
N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Product
UDP [CPD:C00015];
N-acetyl-D-galactosaminyl-alpha-(1->4)-N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Comment
Isolated from Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway.
History
EC 2.4.1.291 created 2012
Orthology
K17248  
N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase
Genes
PUL: 
AMAL: 
AMAE: 
AMAO: 
AMAC: 
AMB: 
AMG: 
AMK: 
CJE: 
Cj1127c(pglJ)
CJB: 
CJJ: 
CJU: 
C8J_1067(pglJ)
CJN: 
CJI: 
CJSA_1069(pglJ)
CJM: 
CJM1_1105(pglJ)
CJS: 
CJS3_1173(pglJ)
CJP: 
CJEJ: 
CJEU: 
CJEN: 
CJEI: 
CJER: 
CJV: 
CJY: 
CJQ: 
UC78_1084(pglJ)
CJL: 
CJW: 
CJR: 
CJE1269(pglJ)
CJD: 
CJZ: 
CJX: 
CFF: 
CFT: 
CFV: 
CFX: 
CFZ: 
CAMP: 
CFP: 
CCV: 
CHA: 
CCO: 
CLA: 
Cla_1252(pglJ)
CLR: 
CLM: 
CLQ: 
CLN: 
CLL: 
CCOL: 
CCC: 
CCQ: 
CCF: 
CCY: 
CCOI: 
CCOF: 
CAJ: 
CIS: 
CINS_1217(pglJ)
CVO: 
CVOL_1231(pglJ)
CPEL: 
CPEL_1358(pglJ)
CAMR: 
CSM: 
CSF: 
CGRA: 
CURE: 
ANT: 
SBA: 
HPK: 
FIN: 
RAG: 
LAN: 
ZGA: 
AHZ: 
 » show all
Taxonomy
Reference
1  [PMID:16186480]
  Authors
Glover KJ, Weerapana E, Imperiali B
  Title
In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 14255-9.
  Sequence
[cje:Cj1127c]
Reference
2  [PMID:18034500]
  Authors
Chen MM, Weerapana E, Ciepichal E, Stupak J, Reid CW, Swiezewska E, Imperiali B
  Title
Polyisoprenol specificity in the Campylobacter jejuni N-linked glycosylation pathway.
  Journal
Biochemistry. 46 (2007) 14342-8.
  Sequence
[cje:Cj1127c]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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