KEGG   ENZYME: 2.4.1.293Help
Entry
EC 2.4.1.293                Enzyme                                 

Name
GalNAc5-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase;
PglI
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-glucose:[GalNAc-alpha-(1->4)]4-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol 3-beta-D-glucosyltransferase
Reaction(IUBMB)
UDP-alpha-D-glucose + [GalNAc-alpha-(1->4)]4-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol = UDP  [GalNAc-alpha-(1->4)]2-[Glc-beta-(1->3)]-[GalNAc-alpha-(1->4)]2-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol
Substrate
UDP-alpha-D-glucose [CPD:C00029];
[GalNAc-alpha-(1->4)]4-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol
Product
UDP  [GalNAc-alpha-(1->4)]2-[Glc-beta-(1->3)]-[GalNAc-alpha-(1->4)]2-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol
Comment
Isolated from the bacterium Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway.
History
EC 2.4.1.293 created 2012
Orthology
K17250  
GalNAc5-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase
Genes
CJE: 
Cj1128c(pglI)
CJB: 
CJJ: 
CJU: 
C8J_1068(pglI)
CJN: 
CJI: 
CJSA_1070(pgll)
CJM: 
CJM1_1106(pglI)
CJS: 
CJS3_1174(pglI)
CJP: 
CJEJ: 
CJEU: 
CJEN: 
CJEI: 
CJER: 
CJV: 
CJY: 
CJQ: 
UC78_1085(pglI)
CJL: 
CJW: 
CJR: 
CJE1270(pglI)
CJD: 
CJZ: 
CJX: 
CCV: 
CCO: 
CCOL: 
CCC: 
CCQ: 
CCF: 
CCY: 
CCOI: 
CCOF: 
TSH: 
BCEL: 
FLI: 
TRD: 
CTHI: 
 » show all
Taxonomy
Reference
1  [PMID:16186480]
  Authors
Glover KJ, Weerapana E, Imperiali B
  Title
In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 14255-9.
  Sequence
[cje:Cj1128c]
Reference
2  [PMID:16547029]
  Authors
Kelly J, Jarrell H, Millar L, Tessier L, Fiori LM, Lau PC, Allan B, Szymanski CM
  Title
Biosynthesis of the N-linked glycan in Campylobacter jejuni and addition onto protein through block transfer.
  Journal
J. Bacteriol. 188 (2006) 2427-34.
  Sequence
[cje:Cj1128c]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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