KEGG   ENZYME: 2.4.1.303Help
Entry
EC 2.4.1.303                Enzyme                                 

Name
UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-galactosyltransferase;
WbbD;
WbbD beta3Gal-transferase;
UDP-Gal:GlcNAc-R beta1,3-galactosyltransferase;
UDP-Gal:GlcNAcalpha-pyrophosphate-R beta1,3-galactosyltransferase;
UDP-Gal:GlcNAc-R galactosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-galactose:N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 3-beta-galactosyltransferase
Reaction(IUBMB)
UDP-alpha-D-galactose + N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = UDP + beta-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol [RN:R10432]
Reaction(KEGG)
Substrate
UDP-alpha-D-galactose [CPD:C00052];
N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C01289]
Product
UDP [CPD:C00015];
beta-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol [CPD:C20617]
Comment
The enzyme is involved in the the biosynthesis of the O-polysaccharide repeating unit of Escherichia coli O7:K1 (VW187). Requires Mn2+.
History
EC 2.4.1.303 created 2013
Orthology
K18788  
UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-galactosyltransferase
Genes
ECT: 
EOC: 
CE10_2348(wbbD)
EBR: 
ECB_01936(wbbD)
EBL: 
ECD_01936(wbbD)
EBE: 
B21_01923(ybl89)
Taxonomy
Reference
1  [PMID:15625181]
  Authors
Riley JG, Menggad M, Montoya-Peleaz PJ, Szarek WA, Marolda CL, Valvano MA, Schutzbach JS, Brockhausen I
  Title
The wbbD gene of E. coli strain VW187 (O7:K1) encodes a UDP-Gal: GlcNAc{alpha}-pyrophosphate-R {beta}1,3-galactosyltransferase involved in the biosynthesis of O7-specific lipopolysaccharide.
  Journal
Glycobiology. 15 (2005) 605-13.
  Sequence
Reference
2  [PMID:18536883]
  Authors
Brockhausen I, Riley JG, Joynt M, Yang X, Szarek WA
  Title
Acceptor substrate specificity of UDP-Gal: GlcNAc-R beta1,3-galactosyltransferase (WbbD) from Escherichia coli O7:K1.
  Journal
Glycoconj. J. 25 (2008) 663-73.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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