KEGG   ENZYME: 2.4.1.44Help
Entry
EC 2.4.1.44                 Enzyme                                 

Name
lipopolysaccharide 3-alpha-galactosyltransferase;
UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase;
UDP-galactose:polysaccharide galactosyltransferase;
uridine diphosphate galactose:lipopolysaccharide alpha-3-galactosyltransferase;
uridine diphosphogalactose-lipopolysaccharide alpha,3-galactosyltransferase;
UDP-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase
Reaction(IUBMB)
UDP-alpha-D-galactose + lipopolysaccharide = UDP + 3-alpha-D-galactosyl-[lipopolysaccharide glucose] [RN:R01997]
Reaction(KEGG)
Substrate
UDP-alpha-D-galactose [CPD:C00052];
lipopolysaccharide [CPD:C00338]
Product
UDP [CPD:C00015];
3-alpha-D-galactosyl-[lipopolysaccharide glucose] [CPD:C04473]
Comment
Transfers alpha-D-galactosyl residues to D-glucose in the partially completed core of lipopolysaccharide [cf. EC 2.4.1.56 (lipopolysaccharide N-acetylglucosaminyltransferase), EC 2.4.1.58 (lipopolysaccharide glucosyltransferase I) and EC 2.4.1.73 (lipopolysaccharide glucosyltransferase II)].
History
EC 2.4.1.44 created 1972, modified 2002
Pathway
ec00540  Lipopolysaccharide biosynthesis
ec01100  Metabolic pathways
Orthology
K03278  UDP-D-galactose:(glucosyl)LPS alpha-1,3-D-galactosyltransferase
Genes
STY: STY4077(waaI)
STT: t3801(waaI)
SEX: STBHUCCB_40120
SENT: TY21A_19310
STM: STM3718(rfaI)
SEO: STM14_4479(rfaI)
SEV: STMMW_37071
SEY: SL1344_3684(rfaI)
SEM: STMDT12_C37750
SEJ: STMUK_3704(rfaI)
SEB: STM474_3891(rfaI)
SEF: UMN798_4038(rfaI)
SENR: STMDT2_36041(rfaI)
SEND: DT104_37021(waaI)
SENI: CY43_19290
SPT: SPA3570(waaI)
SEK: SSPA3333
SEI: SPC_3800(waaI)
SEC: SCH_3641(rfaI)
SHB: SU5_04195
SENS: Q786_18180
SED: SeD_A4105
SEG: SG3713(rfaI)
SEL: SPUL_3846(rfaI)
SEGA: SPUCDC_3832(rfaI)
SET: SEN3540(rfaI)
SENA: AU38_18080
SENO: AU37_18270
SENV: AU39_18275
SENQ: AU40_20360
SENL: IY59_18715
SEEP: I137_18450
SENE: IA1_18075
SBG: SBG_3300(waaI)
SBZ: A464_3795
CAMA: F384_19595
EBF: D782_0097
SSZ: SCc_047(rfaI)
ACX: Achr_7000
PUF: UFO1_4191
 » show all
Taxonomy
Reference
1  [PMID:4898284]
  Authors
Endo A, Rothfield L.
  Title
Studies of a phospholipid-requiring bacterial enzyme. I. Purification and properties of uridine diphosphate galactose: lipopolysaccharide alpha-3-galactosyl transferase.
  Journal
Biochemistry. 8 (1969) 3500-7.
Reference
2  [PMID:6403519]
  Authors
Wollin R, Creeger ES, Rothfield LI, Stocker BA, Lindberg AA.
  Title
Salmonella typhimurium mutants defective in UDP-D-galactose:lipopolysaccharide alpha 1,6-D-galactosyltransferase. Structural, immunochemical, and enzymologic studies of rfaB mutants.
  Journal
J. Biol. Chem. 258 (1983) 3769-74.
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.44
IUBMB Enzyme Nomenclature: 2.4.1.44
ExPASy - ENZYME nomenclature database: 2.4.1.44
BRENDA, the Enzyme Database: 2.4.1.44
CAS: 9073-98-7

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