KEGG   ENZYME: 2.4.1.94Help
Entry
EC 2.4.1.94                 Enzyme                                 

Name
protein N-acetylglucosaminyltransferase;
uridine diphosphoacetylglucosamine-protein acetylglucosaminyltransferase;
uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase;
N-acetylglucosaminyltransferase I
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-N-acetyl-D-glucosamine:[protein]-L-asparagine beta-N-acetyl-D-glucosaminyl-transferase
Reaction(IUBMB)
UDP-N-acetyl-D-glucosamine + [protein]-L-asparagine = UDP + [protein]-N4-(N-acetyl-D-glucosaminyl)-L-asparagine [RN:R00417]
Reaction(KEGG)
Substrate
UDP-N-acetyl-D-glucosamine [CPD:C00043];
[protein]-L-asparagine
Product
UDP [CPD:C00015];
[protein]-N4-(N-acetyl-D-glucosaminyl)-L-asparagine
Comment
The acceptor is the asparagine residue in a sequence of the form Asn-Xaa-Thr or Asn-Xaa-Ser.
History
EC 2.4.1.94 created 1978, modified 2010
Reference
1  [PMID:1156375]
  Authors
Khalkhall Z, Marshall RD.
  Title
Glycosylation of ribonuclease A catalysed by rabbit liver extracts.
  Journal
Biochem. J. 146 (1975) 299-307.
Reference
2  [PMID:986874]
  Authors
Khalkhali Z, Marshall RD.
  Title
UDP-N-acetyl-D-glucosamine-asparagine sequon N-acetyl-beta-D-glucosaminyl-transferase-activity in human serum.
  Journal
Carbohydr. Res. 49 (1976) 455-73.
Reference
3  [PMID:795426]
  Authors
Khalkhali Z, Marshall RD, Reuvers F, Habets-Willems C, Boer P.
  Title
Glycosylation in vitro of an asparagine sequon catalysed by preparations of yeast cell membranes.
  Journal
Biochem. J. 160 (1976) 37-41.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
72319-34-7

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