KEGG   ENZYME: 2.4.2.55Help
Entry
EC 2.4.2.55                 Enzyme                                 

Name
nicotinate D-ribonucleotide:phenol phospho-D-ribosyltransferase;
ArsAB
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
BRITE hierarchy
Sysname
nicotinate D-ribonucleotide:phenol phospho-D-ribosyltransferase
Reaction(IUBMB)
nicotinate D-ribonucleotide + phenol = nicotinate + phenyl 5-phospho-alpha-D-ribofuranoside [RN:R10608]
Reaction(KEGG)
Substrate
nicotinate D-ribonucleotide [CPD:C01185];
phenol [CPD:C00146]
Product
nicotinate [CPD:C00253];
phenyl 5-phospho-alpha-D-ribofuranoside [CPD:C20726]
Comment
The enzyme is involved in the biosynthesis of phenolic cobamides in the Gram-positive bacterium Sporomusa ovata. It can also transfer the phospho-D-ribosyl group to 4-methylphenol and 5,6-dimethylbenzimidazole. The related EC 2.4.2.21, nicotinate-nucleotide dimethylbenzimidazole phosphoribosyltransferase, also transfers the phospho-D-ribosyl group from nicotinate D-ribonucleotide to 5,6-dimethylbenzimidazole, but shows no activity with 4-methylphenol or phenol.
History
EC 2.4.2.55 created 2013
Reference
1  [PMID:21696461]
  Authors
Chan CH, Escalante-Semerena JC
  Title
ArsAB, a novel enzyme from Sporomusa ovata activates phenolic bases for adenosylcobamide biosynthesis.
  Journal
Mol. Microbiol. 81 (2011) 952-67.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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