| Entry |
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| Name |
(KDO)2-lipid IVA (2-8) 3-deoxy-D-manno-octulosonic acid transferase;
KDO transferase;
waaA (gene name);
kdtA (gene name);
3-deoxy-D-manno-oct-2-ulosonic acid transferase;
3-deoxy-manno-octulosonic acid transferase
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| Class |
Transferases;
Glycosyltransferases;
Transferring other glycosyl groups
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| Sysname |
CMP-3-deoxy-D-manno-oct-2-ulosonate:(KDO)2-lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase [(2->8) glycosidic bond-forming]
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| Reaction(IUBMB) |
alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-alpha-Kdo = alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP [RN: R09763 R09764]
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| Reaction(KEGG) |
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| Substrate |
alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA;
CMP-alpha-Kdo
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| Product |
alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA [CPD: C19875];
CMP [CPD: C00055]
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| Comment |
The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno-oct-2-ulosonate residues and generate genus-specific epitopes.
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| Orthology |
| 3-deoxy-D-manno-octulosonic-acid transferase |
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| Genes |
ATH: | | ALY: | | GMX: | | MTR: | | CSV: | | RCU: | | POP: | | VVI: | | DOSA: | | BDI: | | SBI: | | SMO: | | PPP: | | ECO: | | ECJ: | | ECD: | | EBW: | | ECOK: | | ECE: | | ECS: | | ECF: | | ETW: | | ELX: | | EOJ: | | EOI: | | EOH: | | ECG: | | EOK: | | ELR: | | ECC: | | ECP: | | ECI: | | ECV: | | ECX: | | ECW: | | ECM: | | ECY: | | ECR: | | ECQ: | | ECK: | | ECT: | | EOC: | | EUM: | | ECZ: | | ELO: | | ELN: | | ELH: | | ESE: | | ESO: | | ESM: | | ESL: | | ECL: | | EBR: | | EBD: | | EKO: | | EKF: | | EAB: | | EDH: | | EDJ: | | EIH: | | ENA: | | ELU: | | EUN: | | ELW: | | ELL: | | ELC: | | ELD: | | ELP: | | EBL: | | EBE: | | ELF: | | ECOA: | | EFE: | | EBT: | | STY: | | STT: | | SEX: | | STM: | | SEO: | | SEV: | | SEY: | | SEM: | | SEJ: | | SEB: | | SEF: | | SETU: | | SPT: | | SEK: | | SPQ: | | SEI: | | SEC: | | SEH: | | SHB: | | SEE: | | SEW: | | SEA: | | SED: | | SEG: | | SEL: | | SET: | | SENJ: | | SES: | | SBG: | | YPE: | | YPK: | | YPA: | | YPN: | | YPM: | | YPP: | | YPG: | | YPZ: | | YPT: | | YPD: | | YPX: | | YPH: | | YPS: | | YPI: | | YPY: | | YPB: | | YEN: | | YEP: | | YEY: | | SFL: | | SFX: | | SFV: | | SFE: | | SSN: | | SSJ: | | SBO: | | SBC: | | SDY: | | ECA: | | PCT: | | PCC: | | PWA: | | PEC: | | ETA: | | EPY: | | EPR: | | EAM: | | EAY: | | EBI: | | ERJ: | | PLU: | | PAY: | | WBR: | | WGL: | | SGL: | | ENT: | | ENC: | | ENO: | | ESC: | | EEC: | | ENL: | | EAS: | | EAE: | | EAR: | | ESA: | | CSK: | | CSZ: | | CTU: | | KPN: | | KPU: | | KPM: | | KPP: | | KPE: | | KPO: | | KVA: | | KOX: | | CKO: | | CRO: | | SPE: | | SRR: | | SRS: | | SRA: | | SSZ: | | SMAF: | | SMW: | | PMR: | | EIC: | | ETR: | | ETD: | | ETC: | | BFL: | | BPN: | | BVA: | | BCHR: | | HDE: | | DDA: | | DDC: | | DDD: | | DZE: | | XBO: | | XNE: | | PAM: | | PLF: | | PAJ: | | PAQ: | | PVA: | | PAO: | | RAH: | | RAQ: | | RAA: | | PSI: | | MMK: | | ROR: | | SECT: | | SEHC: | | EBF: | | HIN: | | HIT: | | HIP: | | HIQ: | | HIF: | | HIL: | | HIU: | | HIE: | | HIZ: | | HDU: | | HAP: | | HPR: | | HSO: | | HSM: | | PMU: | | PMV: | | PUL: | | PMP: | | MSU: | | MHT: | | MHQ: | | MHX: | | APL: | | APJ: | | APA: | | ASU: | | ASI: | | AAP: | | AAT: | | AAO: | | AAN: | | GAN: | | BTO: | | XFA: | | XFT: | | XFM: | | XFN: | | XFF: | | XCC: | | XCB: | | XCA: | | XCV: | | XCP: | | XAC: | | XAX: | | XAO: | | XOO: | | XOM: | | XOP: | | XOR: | | XAL: | | XCI: | | SML: | | SMT: | | BUJ: | | SMZ: | | PSU: | | PSD: | | FAU: | | RHD: | | VCH: | | VCE: | | VCJ: | | VCO: | | VCR: | | VCM: | | VCI: | | VCL: | | VVU: | | VVY: | | VVM: | | VPA: | | VPB: | | VHA: | | VSP: | | VEX: | | VEJ: | | VFU: | | VFI: | | VFM: | | VSA: | | PPR: | | VAN: | | PAE: | | PAU: | | PAP: | | PAG: | | PAF: | | PNC: | | PDK: | | PSG: | | PPU: | | PPF: | | PPG: | | PPW: | | PPT: | | PPB: | | PPI: | | PPX: | | PPUH: | | PPUU: | | PST: | | PSB: | | PSP: | | PFL: | | PFO: | | PFS: | | PFE: | | PFC: | | PPZ: | | PEN: | | PMY: | | PMK: | | PSA: | | PSZ: | | PSR: | | PSC: | | PSJ: | | PSH: | | PBA: | | PFV: | | PDR: | | CJA: | | AVN: | | AVL: | | AVD: | | PAR: | | PCR: | | PRW: | | ACI: | | ACD: | | ACB: | | ABM: | | ABY: | | ABC: | | ABN: | | ABB: | | ABX: | | ABZ: | | ABR: | | ABD: | | ABH: | | ABAD: | | ACC: | | MCT: | | SON: | | SDN: | | SFR: | | SAZ: | | SBL: | | SBM: | | SBN: | | SBP: | | SBT: | | SBS: | | SBB: | | SLO: | | SPC: | | SHP: | | SSE: | | SPL: | | SHE: | | SHM: | | SHN: | | SHW: | | SHL: | | SWD: | | SWP: | | SVO: | | ILO: | | CPS: | | PHA: | | PAT: | | PSM: | | SDE: | | MAQ: | | MHC: | | MAD: | | MBS: | | AMC: | | AMAC: | | AMB: | | AMG: | | AMK: | | AMAA: | | ALT: | | GAG: | | GNI: | | GPS: | | PIN: | | PSY: | | TTU: | | FBL: | | CBU: | | CBS: | | CBD: | | CBG: | | CBC: | | LPN: | | LPU: | | LPF: | | LPP: | | LPC: | | LPA: | | LPE: | | LLO: | | MCA: | | MMT: | | MAH: | | FTU: | | FTF: | | FTW: | | FTR: | | FTT: | | FTG: | | FTL: | | FTH: | | FTA: | | FTS: | | FTI: | | FTM: | | FTN: | | FCF: | | FCN: | | FPH: | | FRT: | | TCX: | | TCY: | | MEJ: | | MEC: | | CYQ: | | NOC: | | NHL: | | NWA: | | ALV: | | TVI: | | TMB: | | AEH: | | HHA: | | TGR: | | TKM: | | TNI: | | HNA: | | HCH: | | CSA: | | HEL: | | ABO: | | ADI: | | KKO: | | MMW: | | MME: | | MPC: | | TOL: | | AHA: | | ASA: | | AVR: | | TAU: | | OCE: | | DNO: | | AFE: | | AFR: | | ACU: | | AFI: | | SAGA: | | RMA: | | VOK: | | GPB: | | NMA: | | NME: | | NMP: | | NMH: | | NMC: | | NMN: | | NMT: | | NMI: | | NMD: | | NMM: | | NMS: | | NMQ: | | NMW: | | NMZ: | | NGO: | | NGK: | | NGT: | | NLA: | | CVI: | | LHK: | | PSE: | | RSO: | | RSC: | | RSL: | | RSN: | | RPI: | | RPF: | | REU: | | REH: | | RME: | | CTI: | | CNC: | | BMA: | | BMV: | | BML: | | BMN: | | BPS: | | BPM: | | BPL: | | BPD: | | BPR: | | BPZ: | | BPQ: | | BTE: | | BVI: | | BUR: | | BCN: | | BCH: | | BCM: | | BCJ: | | BAM: | | BAC: | | BMU: | | BMJ: | | BCT: | | BXE: | | BPH: | | BPY: | | BGL: | | BUG: | | BGE: | | BGF: | | BRH: | | BGD: | | BYI: | | BUK: | | BPX: | | PNU: | | PNE: | | BPE: | | BPC: | | BPER: | | BPA: | | BPAR: | | BBR: | | BBM: | | BBH: | | BPT: | | BAV: | | AXY: | | TEQ: | | TEA: | | TEG: | | TAS: | | TAT: | | PUT: | | AKA: | | RFR: | | POL: | | PNA: | | AAV: | | AJS: | | DIA: | | AAA: | | ACK: | | VEI: | | DAC: | | DEL: | | VAP: | | VPE: | | CTT: | | ADN: | | ADK: | | RTA: | | MPT: | | HAR: | | MMS: | | HSE: | | CFU: | | LCH: | | TIN: | | THI: | | RGE: | | EBA: | | AZO: | | AZA: | | DAR: | | TMZ: | | DSU: | | TBD: | | MFA: | | MMB: | | MEH: | | MEI: | | MEP: | | APP: | | SLT: | | GCA: | | KBL: | | KBT: | | KGA: | | BPRC: | | HPY: | | HEO: | | HPJ: | | HPA: | | HPS: | | HHP: | | HHQ: | | HHR: | | HPG: | | HPP: | | HPB: | | HPL: | | HPC: | | HCA: | | HPM: | | HPE: | | HPO: | | HPI: | | HPQ: | | HPW: | | HPU: | | HEF: | | HPF: | | HEQ: | | HEX: | | HPT: | | HPZ: | | HPV: | | HPX: | | HEN: | | HPH: | | HEG: | | HPN: | | HEP: | | HEU: | | HES: | | HCN: | | HPD: | | HER: | | HEI: | | HPYA: | | HPYK: | | HPYO: | | HPYL: | | HHE: | | HAC: | | HMS: | | HFE: | | HBI: | | HCE: | | HCM: | | HCB: | | WSU: | | TDN: | | SUA: | | SKU: | | SULR: | | CJE: | | CJB: | | CJJ: | | CJU: | | CJN: | | CJI: | | CJM: | | CJS: | | CJP: | | CJR: | | CJD: | | CFF: | | CCV: | | CHA: | | CCO: | | CLA: | | ABU: | | ABT: | | ARC: | | SDL: | | SBA: | | NSA: | | NIS: | | SUN: | | NAM: | | GSU: | | GSK: | | GME: | | GUR: | | GLO: | | GBM: | | GEO: | | GEM: | | GEB: | | PCA: | | PPD: | | DVU: | | DVL: | | DVM: | | DVG: | | DDE: | | DDN: | | DSA: | | DAS: | | DAF: | | DHY: | | DPI: | | LIP: | | LIR: | | DBA: | | DRT: | | BBA: | | BBAT: | | BEX: | | BMX: | | DPS: | | DAK: | | DPR: | | DSF: | | DOL: | | DAL: | | DAT: | | DTO: | | ADE: | | ACP: | | AFW: | | ANK: | | MXA: | | MFU: | | MSD: | | CCX: | | SUR: | | DAO: | | DTI: | | SFU: | | DBR: | | HMR: | | RPR: | | RPO: | | RPW: | | RPZ: | | RPG: | | RPS: | | RPV: | | RPQ: | | RPL: | | RPN: | | RTY: | | RTT: | | RTB: | | RCM: | | RCC: | | RBE: | | RBO: | | RCO: | | RFE: | | RAK: | | RRI: | | RRJ: | | RRA: | | RRC: | | RRH: | | RRB: | | RRN: | | RRP: | | RMS: | | RMI: | | RPK: | | RAF: | | RHE: | | RJA: | | RSV: | | RSW: | | RPH: | | RAU: | | RMO: | | RPP: | | RRE: | | RAM: | | PUB: | | PEL: | | MMN: | | MLO: | | MCI: | | MOP: | | MAM: | | MES: | | PLA: | | SME: | | SMK: | | SMQ: | | SMX: | | SMI: | | SMEG: | | SMEL: | | SMD: | | RHI: | | SFH: | | SFD: | | ATU: | | ARA: | | AVI: | | AGR: | | RET: | | REC: | | RLE: | | RLT: | | RLG: | | RTR: | | LAS: | | LAA: | | LSO: | | LCC: | | BME: | | BMI: | | BMZ: | | BMG: | | BMW: | | BMF: | | BMB: | | BMC: | | BAA: | | BMS: | | BSI: | | BMT: | | BSV: | | BOV: | | BCS: | | BSK: | | BMR: | | BPP: | | OAN: | | BJA: | | BJU: | | BRA: | | BBT: | | BRS: | | RPA: | | RPB: | | RPC: | | RPD: | | RPE: | | RPT: | | RPX: | | NWI: | | NHA: | | OCA: | | OCG: | | OCO: | | AOL: | | BHE: | | BQU: | | BQR: | | BBK: | | BTR: | | BGR: | | BCD: | | BAUS: | | BVN: | | XAU: | | AZC: | | SNO: | | MEX: | | MEA: | | MDI: | | MCH: | | MRD: | | MET: | | MPO: | | MNO: | | MSL: | | HDN: | | HMC: | | RVA: | | MSC: | | CCR: | | CCS: | | CAK: | | CSE: | | PZU: | | BSB: | | AEX: | | SIL: | | SIT: | | RSP: | | RSH: | | RSQ: | | RSK: | | RCP: | | JAN: | | RDE: | | RLI: | | PDE: | | DSH: | | KVU: | | KVL: | | PSF: | | PGA: | | PGL: | | OAT: | | OAR: | | MMR: | | HNE: | | HBA: | | GOX: | | GOH: | | GBE: | | ACR: | | AMV: | | GDI: | | GDJ: | | GXY: | | APT: | | APW: | | APF: | | APU: | | APG: | | APQ: | | APX: | | APZ: | | RRU: | | RRF: | | RCE: | | RPM: | | MAG: | | AZL: | | ALI: | | ABS: | | TMO: | | THAL: | | PBR: | | APB: | | PGV: | | MAI: | | MAN: | | APC: | | APM: | | MGM: | | DIN: | | TNR: | | HOR: | | HAS: | | HPK: | | AAR: | | HHL: | | VPR: | | MED: | | CTR: | | CTD: | | CTF: | | CTRD: | | CTRO: | | CTRT: | | CTA: | | CTY: | | CRA: | | CTRQ: | | CTRX: | | CTRZ: | | CTRP: | | CTLJ: | | CTLX: | | CTLL: | | CTB: | | CTRR: | | CTLF: | | CTLI: | | CTL: | | CTRU: | | CTRL: | | CTRV: | | CTRM: | | CTLA: | | CTLM: | | CTLS: | | CTLZ: | | CTLC: | | CTLN: | | CTLB: | | CTLQ: | | CTO: | | CTRN: | | CTJ: | | CTZ: | | CTG: | | CTK: | | CSW: | | CES: | | CTRB: | | CTRE: | | CTRS: | | CFS: | | CFW: | | CTRF: | | CTN: | | CTQ: | | CTV: | | CTW: | | CTRG: | | CTRI: | | CTRA: | | CTRH: | | CTRJ: | | CTRK: | | CMU: | | CPN: | | CPA: | | CPJ: | | CPT: | | CLP: | | CPM: | | CHP: | | CHB: | | CHS: | | CHI: | | CHT: | | CHC: | | CHR: | | CPSC: | | CPSN: | | CPSB: | | CPSG: | | CPSM: | | CPSI: | | CPSV: | | CPSW: | | CPST: | | CPSD: | | CPSA: | | CCA: | | CAB: | | CFE: | | PCU: | | PUV: | | WCH: | | SNG: | | LIL: | | LIE: | | LIC: | | LBJ: | | LBL: | | LBI: | | LBF: | | TPX: | | BHY: | | BRM: | | BPO: | | BPJ: | | BPIP: | | BPW: | | BIP: | | ABA: | | ACA: | | ACM: | | GMA: | | TSA: | | TRS: | | CTM: | | BTH: | | BFR: | | BFS: | | BFG: | | BVU: | | BHL: | | BXY: | | PGI: | | PGN: | | PGT: | | PDI: | | PPN: | | OSP: | | TFO: | | PRU: | | PMZ: | | PDN: | | PIT: | | PDT: | | AFD: | | ASH: | | CPI: | | NKO: | | PHE: | | PSN: | | SHG: | | SCN: | | HHY: | | SGN: | | CMR: | | BBD: | | EVI: | | CHU: | | DFE: | | SLI: | | LBY: | | RSI: | | FLI: | | EOL: | | FAE: | | MTT: | | GFO: | | FJO: | | FPS: | | FBR: | | FCO: | | FIN: | | COC: | | CCM: | | RBI: | | ZPR: | | CAT: | | RAN: | | RAI: | | RAR: | | RAG: | | RAE: | | FBC: | | CAO: | | CLY: | | WVI: | | KDI: | | LAN: | | ZGA: | | MRS: | | ASL: | | ORH: | | PTQ: | | NDO: | | POM: | | FBA: | | FTE: | | OHO: | | FSU: | | FSC: | | FNU: | | LBA: | | STR: | | IPO: | | OTE: | | CAA: | | MIN: | | AMU: | | GAU: | | RBA: | | PSL: | | PLM: | | PBS: | | IPA: | | SACI: | | PHM: | | EMI: | | TAI: | | ACO: | | TLI: | | AMO: | | CTE: | | CPC: | | CCH: | | CPH: | | CPB: | | CLI: | | PVI: | | PLT: | | PPH: | | PAA: | | CTS: | | IAL: | | AAE: | | HYA: | | HHO: | | HYS: | | HTH: | | HTE: | | TAL: | | SUL: | | SAF: | | PMX: | | TAM: | | DTE: | | TYE: | | NDE: | | LFC: | | LFI: | | DDF: | | DAP: | | CNI: | | FSI: | | TID: | | TOP: | | MOX: | |
» show all
 |
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| Reference |
|
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| Authors |
Lobau S, Mamat U, Brabetz W, Brade H |
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| Title |
Molecular cloning, sequence analysis, and functional characterization of the lipopolysaccharide biosynthetic gene kdtA encoding 3-deoxy-alpha-D-manno-octulosonic acid transferase of Chlamydia pneumoniae strain TW-183. |
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| Journal |
Mol. Microbiol. 18 (1995) 391-9. |
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| Reference |
|
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| Authors |
Mamat U, Baumann M, Schmidt G, Brade H |
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| Title |
The genus-specific lipopolysaccharide epitope of Chlamydia is assembled in C. psittaci and C. trachomatis by glycosyltransferases of low homology. |
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| Journal |
Mol. Microbiol. 10 (1993) 935-41. |
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| Reference |
|
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| Authors |
Belunis CJ, Mdluli KE, Raetz CR, Nano FE |
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| Title |
A novel 3-deoxy-D-manno-octulosonic acid transferase from Chlamydia trachomatis required for expression of the genus-specific epitope. |
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| Journal |
J. Biol. Chem. 267 (1992) 18702-7. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: |
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