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Entry
EC 2.5.1.100                Enzyme                                 

Name
fumigaclavine A dimethylallyltransferase;
FgaPT1
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
dimethylallyl-diphosphate:fumigaclavine A dimethylallyltransferase
Reaction(IUBMB)
fumigaclavine A + dimethylallyl diphosphate = fumigaclavine C + diphosphate [RN:R10201]
Reaction(KEGG)
Substrate
fumigaclavine A [CPD:C20436];
dimethylallyl diphosphate [CPD:C00235]
Product
fumigaclavine C [CPD:C20438];
diphosphate [CPD:C00013]
Comment
Fumigaclavine C is an ergot alkaloid produced by some fungi of the Trichocomaceae family. Activity does not require any metal ions.
History
EC 2.5.1.100 created 2012
Orthology
K14135  
fumigaclavine A dimethylallyltransferase
Genes
AFM: 
Taxonomy
Reference
1  [PMID:16397874]
  Authors
Unsold IA, Li SM
  Title
Reverse prenyltransferase in the biosynthesis of fumigaclavine C in Aspergillus fumigatus: gene expression, purification, and characterization of fumigaclavine C synthase FGAPT1.
  Journal
Chembiochem. 7 (2006) 158-64.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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