KEGG   ENZYME: 2.5.1.105Help
Entry
EC 2.5.1.105                Enzyme                                 

Name
7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase;
MJ0301 (gene name);
dihydropteroate synthase (ambiguous)
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
(7,8-dihydropterin-6-yl)methyl diphosphate:4-(beta-D-ribofuranosyl)aniline 5'-phosphate 6-hydroxymethyl-7,8-dihydropterintransferase
Reaction(IUBMB)
(7,8-dihydropterin-6-yl)methyl diphosphate + 4-(beta-D-ribofuranosyl)aniline 5'-phosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphate [RN:R10339]
Reaction(KEGG)
Substrate
(7,8-dihydropterin-6-yl)methyl diphosphate [CPD:C04807];
4-(beta-D-ribofuranosyl)aniline 5'-phosphate [CPD:C20559]
Product
N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate [CPD:C20562];
diphosphate [CPD:C00013]
Comment
The enzyme, which has been studied in the archaeon Methanocaldococcus jannaschii, is involved in the biosynthesis of tetrahydromethanopterin.
History
EC 2.5.1.105 created 2013
Pathway
ec00790  Folate biosynthesis
Orthology
K06897  7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase
Genes
CRE: CHLREDRAFT_187976
VCN: VOLCADRAFT_89597
MNG: MNEG_10995
TMN: UCRPA7_3213 UCRPA7_8510
FVR: FVEG_12288
FOX: FOXG_13240
NHE: NECHADRAFT_100336 NECHADRAFT_82929
ELA: UCREL1_4419
PSCO: LY89DRAFT_622269
GLZ: GLAREA_09660
ANG: ANI_1_3160024(An02g12600)
ABE: ARB_05789
TVE: TRV_04560
CNB: CNBC0590
STY: STY3078
STT: t2851
STM: STM2950
SENI: CY43_15390
SEI: SPC_2995
SEC: SCH_2881
SHB: SU5_03431
SENS: Q786_14220
SED: SeD_A3263
SEG: SG2853
SEL: SPUL_2951
SET: SEN2789
SENA: AU38_14165
SENO: AU37_14175
SENV: AU39_14175
SENQ: AU40_15945
SENL: IY59_14770
SEEP: I137_14045
SBG: SBG_2565
SBZ: A464_2973
ECLX: LI66_23030
KPE: KPK_0638
KVA: Kvar_0615
KOX: KOX_21210
KOE: A225_3103
EAE: EAE_18700
EAR: CCG30150
CAMA: F384_08620
YEN: YE0055
YEY: Y11_29081
YEW: CH47_3453
YET: CH48_1736
YFR: AW19_3198
YIN: CH53_1837
YKR: CH54_2590
SPE: Spro_0026
SERF: L085_04565
PAJ: PAJ_p0220
PLU: plu1369
PAY: PAU_01378
PMR: PMI1612
XBO: XBJ1_3335
PSI: S70_01420
PSX: DR96_3450
MMK: MU9_1916
ETE: ETEE_3239
VSP: VS_1591
PPR: PBPRB0812(T2851)
SON: SO_A0149
SPL: Spea_2186
SHL: Shal_2159
SWD: Swoo_1375
HBE: BEI_2800
AHA: AHA_4070
ACAV: VI35_01125
SVA: SVA_1427
CVI: CV_1341
TCL: Tchl_0591
SUA: Saut_1887
SDL: Sdel_2136
SMUL: SMUL_2971
NAM: NAMH_1777
GSU: GSU0397
GME: Gmet_3123
GUR: Gura_4225
GLO: Glov_3463
GBM: Gbem_3848
GEO: Geob_0481
GEM: GM21_3932
GEB: GM18_4278
PCA: Pcar_1589
DEU: DBW_1949
DVU: DVU2804
DVL: Dvul_0509
DDE: Dde_1616
DDS: Ddes_1722
DMA: DMR_43120
DGG: DGI_0057
DAS: Daes_0649
DPI: BN4_12371
PPRF: DPRO_2171
DSF: UWK_00265
SAT: SYN_01177
BJA: bll2990
BBT: BBta_5036
BRAD: BF49_5957
RPD: RPD_2374
SNO: Snov_1012
MEX: Mext_3934
MDI: METDI4926
MCH: Mchl_4302
MET: M446_5934
MPO: Mpop_1064
META: Y590_19565
BID: Bind_0186
MSL: Msil_0782
HDN: Hden_0721
CAK: Caul_4116
MALG: MALG_03953
SAL: Sala_0072
BATR: TD68_17380
BMEG: BG04_5883
BEO: BEH_21495
ASOC: CB4_01973
LME: LEUM_1912
LMM: MI1_08340
LMK: LMES_1667
CAC: CA_C0535
CAE: SMB_G0547
CAY: CEA_G0548
CPE: CPE0924
CPF: CPF_1168
CPR: CPR_0999
CTC: CTC_02162
CBK: CLL_A2950
CBN: CbC4_1381
CBT: CLH_2702
CPAS: Clopa_0535
CBV: U729_2526
CTYK: CTK_C22630
AMT: Amet_1418
HSC: HVS_02195
BHU: bhn_I0566
CCT: CC1_27430
CPY: Cphy_0446
CPRO: CPRO_27560
SWO: Swol_0924
SLP: Slip_1371
DSY: DSY3614
DHD: Dhaf_1765
DAE: Dtox_1747
DAU: Daud_1155
SGY: Sgly_1415
ELM: ELI_2165
EHL: EHLA_0786
BPRS: CK3_09180
TTE: TTE1889
THX: Thet_1784
TIT: Thit_1676
MTA: Moth_1430
ADG: Adeg_1793
CSC: Csac_1140
ATE: Athe_0500
TSH: Tsac_2357
MHG: MHY_23700
PUF: UFO1_3670
EUC: EC1_07870
AGL: PYTT_2521
BRM: Bmur_1138
SUS: Acid_3502
FSC: FSU_1848
BTH: BT_1410
BFR: BF3996
BXY: BXY_43840
PRU: PRU_1317
DORI: FH5T_20235
CTE: CT0187
CPC: Cpar_1856
CLI: Clim_0249
PVI: Cvib_1583
PLT: Plut_1937
PAA: Paes_0773
TTK: TST_1111
TMA: TM1679
TMW: THMA_1721
TMQ: THMB_1721
TMX: THMC_1721
TPT: Tpet_0975
TRQ: TRQ2_1154
TNA: CTN_1091
TNP: Tnap_1127
TLE: Tlet_1322
TME: Tmel_1227
TAF: THA_1480
THER: Y592_00645
PMO: Pmob_1890
DTN: DTL3_1038
KOL: Kole_0930
DTU: Dtur_0535
MOX: DAMO_1944
MMP: MMP0581
MMD: GYY_03575
MAE: Maeo_0515
MVO: Mvol_0911
MTHE: MSTHC_1550
MTHR: MSTHT_1738
MBU: Mbur_2076
MMET: MCMEM_0276
MPY: Mpsy_0770
MTP: Mthe_0561
MCJ: MCON_0701
MHU: Mhun_1960
MLA: Mlab_1747
MPI: Mpet_2355
MPD: MCP_0534(mptH)
MEZ: Mtc_0920
RCI: RCIX2724
MTH: MTH_1101
METC: MTCT_0995
METE: tca_01058
METH: MBMB1_0309
MCUB: MCBB_1920
HALH: HTSR_1364
HHSR: HSR6_1436
HUT: Huta_1818
MARC: AR505_0012
PHO: PH0874(PH0874) PH1079(PH1079) PH1382(PH1382)
PFU: PF2022
PFI: PFC_08450
TON: TON_0357
TSI: TSIB_0702
THM: CL1_0289
TLT: OCC_02672
TEU: TEU_07665
PPAC: PAP_06080
IHO: Igni_0976
TAG: Tagg_0077
HBU: Hbut_0276
STO: STK_06550
MSE: Msed_1236
AHO: Ahos_0221
PAI: PAE1703
PIS: Pisl_1697
PAS: Pars_0786
POG: Pogu_1547
CMA: Cmaq_0970
ASC: ASAC_0991
NEV: NTE_03244
KCR: Kcr_0391
BARB: AOA66_0223
 » show all
Taxonomy
Reference
1  [PMID:10426953]
  Authors
Xu H, Aurora R, Rose GD, White RH
  Title
Identifying two ancient enzymes in Archaea using predicted secondary structure alignment.
  Journal
Nat. Struct. Biol. 6 (1999) 750-4.
  Sequence
[mja:MJ_0301]
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.105
IUBMB Enzyme Nomenclature: 2.5.1.105
ExPASy - ENZYME nomenclature database: 2.5.1.105
BRENDA, the Enzyme Database: 2.5.1.105

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