KEGG   ENZYME: 2.5.1.121Help
Entry
EC 2.5.1.121                Enzyme                                 

Name
5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase;
PpzP;
dihydrophenazine-1-carboxylate dimethylallyltransferase;
5,10-dihydrophenazine 1-carboxylate dimethylallyltransferase
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
dimethylallyl diphosphate:5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase
Reaction(IUBMB)
dimethylallyl diphosphate + 5,10-dihydrophenazine-1-carboxylate = diphosphate + 9-(dimethylallyl)-5,10-dihydrophenazine-1-carboxylate [RN:R10966]
Reaction(KEGG)
Substrate
dimethylallyl diphosphate [CPD:C00235];
5,10-dihydrophenazine-1-carboxylate [CPD:C20981]
Product
diphosphate [CPD:C00013];
9-(dimethylallyl)-5,10-dihydrophenazine-1-carboxylate [CPD:C20982]
Comment
The enzyme is involved in the biosynthesis of prenylated phenazines by the bacterium Streptomyces anulatus. It is specific for both dimethylallyl diphosphate and 5,10-dihydrophenazine-1-carboxylate.
History
EC 2.5.1.121 created 2014
Reference
1  [PMID:19339241]
  Authors
Saleh O, Gust B, Boll B, Fiedler HP, Heide L
  Title
Aromatic prenylation in phenazine biosynthesis: dihydrophenazine-1-carboxylate dimethylallyltransferase from Streptomyces anulatus.
  Journal
J. Biol. Chem. 284 (2009) 14439-47.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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