KEGG   ENZYME: 2.5.1.70Help
Entry
EC 2.5.1.70                 Enzyme                                 

Name
naringenin 8-dimethylallyltransferase;
N8DT
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
dimethylallyl-diphosphate:naringenin 8-dimethylallyltransferase
Reaction(IUBMB)
dimethylallyl diphosphate + (-)-(2S)-naringenin = diphosphate + sophoraflavanone B [RN:R08951]
Reaction(KEGG)
Substrate
dimethylallyl diphosphate [CPD:C00235];
(-)-(2S)-naringenin [CPD:C00509]
Product
diphosphate [CPD:C00013];
sophoraflavanone B [CPD:C18023]
Comment
Requires Mg2+. This membrane-bound protein is located in the plastids [2]. In addition to naringenin, the enzyme can prenylate several other flavanones at the C-8 position, but more slowly. Along with EC 1.14.13.103 (8-dimethylallylnaringenin 2'-hydroxylase) and EC 2.5.1.71 (leachianone G 2''-dimethylallyltransferase), this enzyme forms part of the sophoraflavanone-G-biosynthesis pathway.
History
EC 2.5.1.70 created 2007
Reference
1  [PMID:10975499]
  Authors
Yamamoto H, Senda M, Inoue K.
  Title
Flavanone 8-dimethylallyltransferase in Sophora flavescens cell suspension cultures.
  Journal
Phytochemistry. 54 (2000) 649-55.
Reference
2  [PMID:14551337]
  Authors
Zhao P, Inoue K, Kouno I, Yamamoto H.
  Title
Characterization of leachianone G 2"-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures.
  Journal
Plant. Physiol. 133 (2003) 1306-13.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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