KEGG   ENZYME: 2.5.1.79Help
Entry
EC 2.5.1.79                 Enzyme                                 

Name
thermospermine synthase;
TSPMS;
ACL5;
SAC51
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
S-adenosyl 3-(methylthio)propylamine:spermidine 3-aminopropyltransferase (thermospermine synthesizing)
Reaction(IUBMB)
S-adenosyl 3-(methylthio)propylamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+ [RN:R09531]
Reaction(KEGG)
Substrate
S-adenosyl 3-(methylthio)propylamine [CPD:C01137];
spermidine [CPD:C00315]
Product
S-methyl-5'-thioadenosine [CPD:C00170];
thermospermine [CPD:C19669];
H+ [CPD:C00080]
Comment
This enzyme is crucial for the proper functioning of xylem vessel elements in the vascular tissues of plants [3].
History
EC 2.5.1.79 created 2010, modified 2013
Orthology
K18787  
thermospermine synthase
Genes
ATH: 
AT5G19530(ACL5)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0006s23880g(POPTRDRAFT_717791) POPTR_0008s15120g(POPTRDRAFT_1085365) POPTR_0010s09940g(POPTRDRAFT_231244)
VVI: 
SLY: 
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
4328835(OJ1077_A12.30)
DOSA: 
Os02t0237100-01(Os02g0237100)
OBR: 
BDI: 
SBI: 
SORBI_02g025980(SORBIDRAFT_02g025980)
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
BPG: 
MIS: 
MPP: 
CSL: 
CME: 
GSL: 
CCP: 
TPS: 
AAF: 
PIF: 
PSOJ: 
EHX: 
GTT: 
 » show all
Taxonomy
Reference
1  [PMID:19075322]
  Authors
Romer P, Faltermeier A, Mertins V, Gedrange T, Mai R, Proff P
  Title
Investigations about N-aminopropyl transferases probably involved in biomineralization.
  Journal
J. Physiol. Pharmacol. 59 Suppl 5 (2008) 27-37.
Reference
2  [PMID:17560575]
  Authors
Knott JM, Romer P, Sumper M
  Title
Putative spermine synthases from Thalassiosira pseudonana and Arabidopsis thaliana synthesize thermospermine rather than spermine.
  Journal
FEBS. Lett. 581 (2007) 3081-6.
  Sequence
[ath:AT5G19530]
Reference
3  [PMID:18599510]
  Authors
Muniz L, Minguet EG, Singh SK, Pesquet E, Vera-Sirera F, Moreau-Courtois CL, Carbonell J, Blazquez MA, Tuominen H
  Title
ACAULIS5 controls Arabidopsis xylem specification through the prevention of premature cell death.
  Journal
Development. 135 (2008) 2573-82.
  Sequence
[ath:AT5G19530]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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