KEGG   ENZYME: 2.5.1.79Help
Entry
EC 2.5.1.79                 Enzyme                                 
Name
thermospermine synthase;
TSPMS;
ACL5;
SAC51
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
S-adenosylmethioninamine:spermidine 3-aminopropyltransferase (thermospermine synthesizing)
Reaction(IUBMB)
S-adenosylmethioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+ [RN:R09531]
Reaction(KEGG)
Substrate
S-adenosylmethioninamine [CPD:C01137];
spermidine [CPD:C00315]
Product
S-methyl-5'-thioadenosine [CPD:C00170];
thermospermine [CPD:C19669];
H+ [CPD:C00080]
Comment
This enzyme is required for correct xylem specification through regulation of the lifetime of the xylem elements [3].
Reference
1  [PMID:19075322]
  Authors
Romer P, Faltermeier A, Mertins V, Gedrange T, Mai R, Proff P
  Title
Investigations about N-aminopropyl transferases probably involved in biomineralization.
  Journal
J. Physiol. Pharmacol. 59 Suppl 5 (2008) 27-37.
  Organism
Thalassiosira pseudonana [GN:tps], Cyclotella meneghiniana
Reference
2  [PMID:17560575]
  Authors
Knott JM, Romer P, Sumper M
  Title
Putative spermine synthases from Thalassiosira pseudonana and Arabidopsis thaliana synthesize thermospermine rather than spermine.
  Journal
FEBS. Lett. 581 (2007) 3081-6.
  Organism
Arabidopsis thaliana [GN:ath], Thalassiosira pseudonana [GN:tps]
Reference
3  [PMID:18599510]
  Authors
Muniz L, Minguet EG, Singh SK, Pesquet E, Vera-Sirera F, Moreau-Courtois CL, Carbonell J, Blazquez MA, Tuominen H
  Title
ACAULIS5 controls Arabidopsis xylem specification through the prevention of premature cell death.
  Journal
Development. 135 (2008) 2573-82.
  Organism
Arabidopsis thaliana [GN:ath]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
DBGET integrated database retrieval system