| Entry |
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| Name |
pseudaminic acid synthase;
PseI;
NeuB3
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| Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
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| Sysname |
phosphoenolpyruvate:2,4-bis(acetylamino)-2,4,6-trideoxy-beta-L-altropyranose transferase (phosphate-hydrolysing, 2,7-acetylamino-transfering, 2-carboxy-2-oxoethyl-forming)
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| Reaction(IUBMB) |
phosphoenolpyruvate + 2,4-bis(acetylamino)-2,4,6-trideoxy-beta-L-altropyranose + H2O = 5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid + phosphate [RN: R09841]
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| Reaction(KEGG) |
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| Substrate |
phosphoenolpyruvate [CPD: C00074];
2,4-bis(acetylamino)-2,4,6-trideoxy-beta-L-altropyranose;
H2O [CPD: C00001]
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| Product |
5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid [CPD: C20082];
phosphate [CPD: C00009]
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| Comment |
The enzyme requires a divalent metal ion, the highest activity values are observed in the presence of Mn2+ and Co2+ (10 mM).
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| Pathway |
| Amino sugar and nucleotide sugar metabolism |
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| Orthology |
| pseudaminic acid synthase |
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| Genes |
AMG: | | PSE: | | HPY: | | HEO: | | HPJ: | | HPA: | | HPS: | | HHP: | | HHQ: | | HHR: | | HPG: | | HPP: | | HPB: | | HPL: | | HPC: | | HCA: | | HPM: | | HPE: | | HPO: | | HPI: | | HPQ: | | HPW: | | HPU: | | HEF: | | HPF: | | HEQ: | | HEX: | | HPT: | | HPZ: | | HPV: | | HPX: | | HEN: | | HPH: | | HEG: | | HPN: | | HEP: | | HEU: | | HES: | | HCN: | | HPD: | | HEY: | | HER: | | HEI: | | HPYA: | | HPYK: | | HPYO: | | HPYL: | | HHE: | | HAC: | | HMS: | | HFE: | | HBI: | | HCE: | | HCM: | | HCP: | | HCB: | | WSU: | | SUA: | | SKU: | | SULR: | | CJE: | | CJB: | | CJJ: | | CJU: | | CJN: | | CJI: | | CJM: | | CJS: | | CJP: | | CJR: | | CJD: | | CCV: | | CLA: | | ABU: | | ABT: | | ANT: | | SDL: | | SBA: | | NAM: | | DSF: | | HMR: | | CAC: | | CAE: | | CAY: | | CNO: | | CTH: | | CBO: | | CBA: | | CBH: | | CBY: | | CBL: | | CBK: | | CBI: | | CBT: | | CBJ: | | CBE: | | CLJ: | | CSR: | | AOE: | | DOR: | | TMT: | | BFG: | | BHL: | | GFO: | | FIN: | | CAT: | | FTE: | | HTH: | | HTE: | | DAP: | | CNI: | | TID: | | MPY: | | MSI: | |
» show all
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| Reference |
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| Authors |
Chou WK, Dick S, Wakarchuk WW, Tanner ME |
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| Title |
Identification and characterization of NeuB3 from Campylobacter jejuni as a pseudaminic acid synthase. |
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| Journal |
J. Biol. Chem. 280 (2005) 35922-8. |
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| Organism |
Campylobacter jejuni [GN: cje] |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: |
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