| Entry |
|
| Name |
4-hydroxyglutamate transaminase;
4-hydroxyglutamate aminotransferase |
| Class |
Transferases;
Transferring nitrogenous groups;
Transaminases
 |
| Sysname |
4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase |
| Reaction(IUBMB) |
4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate +
L-glutamate [RN:R03266] |
| Reaction(KEGG) |
R03266 > R05052
 |
| Substrate |
4-hydroxy-L-glutamate [CPD:C03079];
2-oxoglutarate [CPD:C00026] |
| Product |
4-hydroxy-2-oxoglutarate [CPD:C01127];
L-glutamate [CPD:C00025] |
| Comment |
Oxaloacetate can replace 2-oxoglutarate. This enzyme may be
identical with EC 2.6.1.1 aspartate transaminase. |
| Pathway |
ec00330 Arginine and proline metabolism |
Reference Authors Title
Journal Organism
|
1 [PMID:13948827]
GOLDSTONE A, ADAMS E.
Metabolism of gamma-hydroxyglutamic acid. I. Conversion to
alpha-hydroxy-gamma-ketoglutarate by purified glutamic-aspartic
transaminase to rat liver.
J. Biol. Chem. 237 (1962) 3476-85.
Rattus norvegicus [GN:rno] |
Reference Authors Title
Journal Organism
|
2 [PMID:14089443]
KURATOMI K, FUKUNAGA K, KOBAYASHI Y.
THE METABOLISM OF GAMMA-HYDROXYGLUTAMATE IN RAT LIVER. II. A
TRANSAMINASE CONCERNED IN GAMMA-HYDROXYGLUTAMATE METABOLISM.
Biochim. Biophys. Acta. 78 (1963) 629-36.
Rattus norvegicus [GN:rno] |
| Other DBs |
ExplorEnz - The Enzyme Database: 2.6.1.23
IUBMB Enzyme Nomenclature: 2.6.1.23
ExPASy - ENZYME nomenclature database: 2.6.1.23
BRENDA, the Enzyme Database: 2.6.1.23
CAS: 37277-86-4 |