KEGG   ENZYME: 2.6.1.23Help
Entry
EC 2.6.1.23                 Enzyme                                 

Name 4-hydroxyglutamate transaminase;
4-hydroxyglutamate aminotransferase
Class Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname 4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase
Reaction(IUBMB) 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate +
L-glutamate [RN:R03266]
Reaction(KEGG) R03266 > R05052
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Substrate 4-hydroxy-L-glutamate [CPD:C03079];
2-oxoglutarate [CPD:C00026]
Product 4-hydroxy-2-oxoglutarate [CPD:C01127];
L-glutamate [CPD:C00025]
Comment Oxaloacetate can replace 2-oxoglutarate. This enzyme may be
identical with EC 2.6.1.1 aspartate transaminase.
Pathway ec00330  Arginine and proline metabolism
Reference
  Authors
  Title


  Journal
  Organism
1  [PMID:13948827]
GOLDSTONE A, ADAMS E.
Metabolism of gamma-hydroxyglutamic acid. I. Conversion to
alpha-hydroxy-gamma-ketoglutarate by purified glutamic-aspartic
transaminase to rat liver.
J. Biol. Chem. 237 (1962) 3476-85.
Rattus norvegicus [GN:rno]
Reference
  Authors
  Title

  Journal
  Organism
2  [PMID:14089443]
KURATOMI K, FUKUNAGA K, KOBAYASHI Y.
THE METABOLISM OF GAMMA-HYDROXYGLUTAMATE IN RAT  LIVER. II. A
TRANSAMINASE CONCERNED IN GAMMA-HYDROXYGLUTAMATE METABOLISM.
Biochim. Biophys. Acta. 78 (1963) 629-36.
Rattus norvegicus [GN:rno]
Other DBs ExplorEnz - The Enzyme Database: 2.6.1.23
IUBMB Enzyme Nomenclature: 2.6.1.23
ExPASy - ENZYME nomenclature database: 2.6.1.23
BRENDA, the Enzyme Database: 2.6.1.23
CAS: 37277-86-4

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