KEGG   ENZYME: 2.6.1.24Help
Entry
EC 2.6.1.24                 Enzyme                                 

Name
diiodotyrosine transaminase;
diiodotyrosine aminotransferase;
halogenated tyrosine aminotransferase;
halogenated tyrosine transaminase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
3,5-diiodo-L-tyrosine:2-oxoglutarate aminotransferase
Reaction(IUBMB)
3,5-diiodo-L-tyrosine + 2-oxoglutarate = 4-hydroxy-3,5-diiodophenylpyruvate + L-glutamate [RN:R03207]
Reaction(KEGG)
Substrate
3,5-diiodo-L-tyrosine [CPD:C01060];
2-oxoglutarate [CPD:C00026]
Product
4-hydroxy-3,5-diiodophenylpyruvate;
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein. Also acts on 3,5-dichloro-, 3,5-dibromo- and 3-iodo-L-tyrosine, thyroxine and triiodothyronine.
History
EC 2.6.1.24 created 1972 (EC 2.6.1.25 created 1972, incorporated 1972)
Reference
1  [PMID:4381052]
  Authors
Nakano M.
  Title
Purification and properties of halogenated tyrosine and thyroid hormone transaminase from rat kidney mitochondria.
  Journal
J. Biol. Chem. 242 (1967) 73-81.
  Organism
Rattus norvegicus
Reference
2  [PMID:14159298]
  Authors
NAKANO M, DANOWSKI TS.
  Title
THYROID-HORMONE TRANSAMINASE AND OXIDASE IN RAT-KIDNEY MITOCHONDRIA.
  Journal
Biochim. Biophys. Acta. 85 (1964) 18-28.
  Organism
Rattus norvegicus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9033-18-5

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