| Entry |
|
| Name |
diiodotyrosine transaminase;
diiodotyrosine aminotransferase;
halogenated tyrosine aminotransferase;
halogenated tyrosine transaminase
|
| Class |
Transferases;
Transferring nitrogenous groups;
Transaminases
 |
| Sysname |
3,5-diiodo-L-tyrosine:2-oxoglutarate aminotransferase
|
| Reaction(IUBMB) |
3,5-diiodo-L-tyrosine + 2-oxoglutarate = 4-hydroxy-3,5-diiodophenylpyruvate + L-glutamate [RN: R03207]
|
| Reaction(KEGG) |
|
| Substrate |
3,5-diiodo-L-tyrosine [CPD: C01060];
2-oxoglutarate [CPD: C00026]
|
| Product |
4-hydroxy-3,5-diiodophenylpyruvate;
L-glutamate [CPD: C00025]
|
| Comment |
A pyridoxal-phosphate protein. Also acts on 3,5-dichloro-, 3,5-dibromo- and 3-iodo-L-tyrosine, thyroxine and triiodothyronine.
|
| Reference |
|
| Authors |
Nakano M. |
| Title |
Purification and properties of halogenated tyrosine and thyroid hormone transaminase from rat kidney mitochondria. |
| Journal |
J. Biol. Chem. 242 (1967) 73-81. |
| Organism |
Rattus norvegicus [GN: rno] |
| Reference |
|
| Authors |
NAKANO M, DANOWSKI TS. |
| Title |
THYROID-HORMONE TRANSAMINASE AND OXIDASE IN RAT-KIDNEY MITOCHONDRIA. |
| Journal |
Biochim. Biophys. Acta. 85 (1964) 18-28. |
| Organism |
Rattus norvegicus [GN: rno] |
| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 9033-18-5 |