KEGG   ENZYME: 2.6.1.36Help
Entry
EC 2.6.1.36                 Enzyme                                 
Name
L-lysine 6-transaminase;
lysine 6-aminotransferase;
lysine epsilon-aminotransferase;
lysine epsilon-transaminase;
lysine:2-ketoglutarate 6-aminotransferase;
L-lysine-alpha-ketoglutarate aminotransferase;
L-lysine-alpha-ketoglutarate 6-aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
L-lysine:2-oxoglutarate 6-aminotransferase
Reaction(IUBMB)
L-lysine + 2-oxoglutarate = (S)-2-amino-6-oxohexanoate + L-glutamate [RN:R00457]
Reaction(KEGG)
Substrate
L-lysine [CPD:C00047];
2-oxoglutarate [CPD:C00026]
Product
(S)-2-amino-6-oxohexanoate [CPD:C04076];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein. The product (L-allysine) is converted into the intramolecularly dehydrated form, (S)-2,3,4,5-tetrahydropyridine-2-carboxylate.
Pathway
Metabolic pathways
Orthology
K03918  
L-lysine 6-transaminase
Genes
PCA: 
DPS: 
AEX: 
MTU: 
Rv3290c(lat)
MTV: 
MTC: 
MT3389(lat)
MRA: 
MTF: 
MTB: 
MTK: 
MTZ: 
TBXG_003318
MTG: 
MRGA327_20240
MTE: 
CCDC5079_3037
MTL: 
CCDC5180_2999
MTO: 
MTCTRI2_3357(lat)
MTD: 
UDA_3290c(lat)
MTN: 
ERDMAN_3606(lat)
MTJ: 
J112_17680
MTUB: 
MT7199_3332
MBO: 
Mb3318c(lat)
MBB: 
BCG_3319c(lat) BCG_3354c(lat')
MBT: 
JTY_3315(lat)
MBM: 
BCGMEX_3317c(lat) BCGMEX_3352c(lat')
MBK: 
K60_034200 K60_040930 K60_041270
MAF: 
MAF_33010(lat)
MCE: 
MCAN_33131(lat)
MCQ: 
BN44_70081(lat)
MCV: 
BN43_60305(lat)
MCX: 
BN42_41348(lat)
MCZ: 
BN45_60328(lat)
MPA: 
MAP3410c(lat)
MAV: 
MAV_4262
MIT: 
OCO_41280
MIR: 
OCQ_42550
MIA: 
OCU_41200
MID: 
MIP_06217
MSM: 
MSMEG_1764
MSG: 
MSMEI_1721(lat)
MSA: 
Mycsm_01310
MUL: 
MUL_2644(lat)
MVA: 
Mvan_1652
MGI: 
Mflv_4796
MSP: 
Mspyr1_42060
MAB: 
MAB_3646c
MMV: 
MYCMA_2002(lat)
MMC: 
Mmcs_1272
MKM: 
Mkms_1289
MJL: 
Mjls_1301
MMI: 
MMAR_1243(lat)
MRH: 
MycrhN_0460
MMM: 
W7S_20600
MCB: 
Mycch_1253
MLI: 
MULP_01403(lat)
ASD: 
AS9A_4565
NFA: 
nfa9840
NCY: 
NOCYR_1048(lat)
NBR: 
O3I_005745
RHA: 
RHA1_ro06277(lat)
RER: 
RER_21100(lat)
ROP: 
ROP_63400(lat)
REQ: 
REQ_33980
SRT: 
Srot_1934
SCT: 
SCAT_5685(lat)
SCY: 
SCATT_56850
IVA: 
Isova_2511
MPH: 
MLP_13250(lat)
SRO: 
Sros_7678
FRA: 
Francci3_2873
FRE: 
Franean1_2373
FRI: 
FraEuI1c_2435
FAL: 
FRAAL4414(lat)
FSY: 
FsymDg_2929
SEN: 
SACE_0784(lat)
TBI: 
Tbis_2682
PPN: 
Palpr_0480
SRU: 
SRU_0799
SRM: 
SRM_00977(argD)
RMR: 
Rmar_2194
RMG: 
Rhom172_0680
PHE: 
Phep_1211
SHG: 
Sph21_3678
SCN: 
Solca_2439
WVI: 
Weevi_0195
FBA: 
FIC_01043
TAI: 
Taci_1141
TLI: 
Tlie_0683
AMO: 
Anamo_0517
IAL: 
IALB_1476(lat)
STI: 
Sthe_2786
TTR: 
Tter_1717
ABI: 
Aboo_0464
ACF: 
AciM339_0584
 » show all
Taxonomy
Reference
1  [PMID:5722275]
  Authors
Soda K, Misono H, Yamamoto T.
  Title
L-Lysine:alpha-ketoglutarate aminotransferase. I. Identification of a product, delta-1-piperideine-6-carboxylic acid.
  Journal
Biochemistry. 7 (1968) 4102-9.
  Organism
Flavobacterium fuscum
Reference
2  [PMID:5722276]
  Authors
Soda K, Misono H.
  Title
L-Lysine:alpha-ketoglutarate aminotransferase. II. Purification, crystallization, and properties.
  Journal
Biochemistry. 7 (1968) 4110-9.
  Organism
Achrornobacter liquidurn, Flavobacterium flavescens, Flavobacterium fuscum
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9054-68-6
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