KEGG   ENZYME: 2.6.1.36Help
Entry
EC 2.6.1.36                 Enzyme                                 

Name
L-lysine 6-transaminase;
lysine 6-aminotransferase;
lysine epsilon-aminotransferase;
lysine epsilon-transaminase;
lysine:2-ketoglutarate 6-aminotransferase;
L-lysine-alpha-ketoglutarate aminotransferase;
L-lysine-alpha-ketoglutarate 6-aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
L-lysine:2-oxoglutarate 6-aminotransferase
Reaction(IUBMB)
L-lysine + 2-oxoglutarate = (S)-2-amino-6-oxohexanoate + L-glutamate [RN:R00457]
Reaction(KEGG)
Substrate
L-lysine [CPD:C00047];
2-oxoglutarate [CPD:C00026]
Product
(S)-2-amino-6-oxohexanoate [CPD:C04076];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein. The product (L-allysine) is converted into the intramolecularly dehydrated form, (S)-2,3,4,5-tetrahydropyridine-2-carboxylate.
History
EC 2.6.1.36 created 1972, modified 2011
Pathway
Metabolic pathways
Orthology
K03918  
L-lysine 6-transaminase
Genes
PCA: 
BMX: 
DPS: 
AEX: 
MTU: 
Rv3290c(lat)
MTV: 
MTC: 
MT3389(lat)
MRA: 
MTF: 
MTB: 
MTK: 
MTZ: 
MTG: 
MTE: 
MTUR: 
MTL: 
MTO: 
MTD: 
MTN: 
MTJ: 
MTUB: 
MTUC: 
MTUE: 
MTX: 
MTUH: 
MTUL: 
MTUT: 
MTUU: 
MTQ: 
MBO: 
Mb3318c(lat)
MBB: 
BCG_3319c(lat) BCG_3354c(lat')
MBT: 
MBM: 
MBK: 
MBZ: 
MAF: 
MCE: 
MCQ: 
MCV: 
MCX: 
MCZ: 
MPA: 
MAO: 
MAV: 
MAVR: 
MAVD: 
MIT: 
MIR: 
MIA: 
MIE: 
MID: 
MYO: 
MSM: 
MSG: 
MSB: 
MSA: 
MSN: 
MSH: 
MUL: 
MVA: 
MGI: 
MSP: 
MAB: 
MABB: 
MMV: 
MAK: 
MAY: 
MAZ: 
MMC: 
MKM: 
MJL: 
MMI: 
MRH: 
MMM: 
MCB: 
MLI: 
MKN: 
MNE: 
ASD: 
NFA: 
NCY: 
NBR: 
NNO: 
RHA: 
RER: 
REY: 
ROP: 
ROA: 
REQ: 
RPY: 
SRT: 
SCT: 
SCY: 
IVA: 
MPH: 
SRO: 
FRA: 
FRE: 
FRI: 
FAL: 
FSY: 
SEN: 
TBI: 
TAI: 
TLI: 
AMO: 
PPN: 
SRU: 
SRM: 
SRM_00977(argD)
RMR: 
RMG: 
PHE: 
SHG: 
SHT: 
SCN: 
WVI: 
EAO: 
FBA: 
IAL: 
MRO: 
STI: 
TTR: 
ABI: 
ACF: 
 » show all
Taxonomy
Reference
1  [PMID:5722275]
  Authors
Soda K, Misono H, Yamamoto T.
  Title
L-Lysine:alpha-ketoglutarate aminotransferase. I. Identification of a product, delta-1-piperideine-6-carboxylic acid.
  Journal
Biochemistry. 7 (1968) 4102-9.
Reference
2  [PMID:5722276]
  Authors
Soda K, Misono H.
  Title
L-Lysine:alpha-ketoglutarate aminotransferase. II. Purification, crystallization, and properties.
  Journal
Biochemistry. 7 (1968) 4110-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9054-68-6

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