KEGG   ENZYME: 2.6.1.79Help
Entry
EC 2.6.1.79                 Enzyme                                 

Name
glutamate---prephenate aminotransferase;
prephenate transaminase (ambiguous);
PAT (ambiguous);
L-glutamate:prephenate aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
L-arogenate:2-oxoglutarate aminotransferase
Reaction(IUBMB)
L-arogenate + 2-oxoglutarate = prephenate + L-glutamate [RN:R07276]
Reaction(KEGG)
Substrate
L-arogenate [CPD:C00826];
2-oxoglutarate [CPD:C00026]
Product
prephenate [CPD:C00254];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein. Aspartate can also act as the amino donor, but more slowly (cf. EC 2.6.1.78, aspartate---prephenate aminotransferase). The enzyme from higher plants shows a marked preference for prephenate as substrate compared to pyruvate, phenylpyruvate or 4-hydroxyphenylpyruvate [1].
History
EC 2.6.1.79 created 2005
Pathway
Phenylalanine, tyrosine and tryptophan biosynthesis
Metabolic pathways
Orthology
K15849  
bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase
Genes
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
POPTR_0005s08100g(POPTRDRAFT_760138) POPTR_0007s05880g(POPTRDRAFT_819830)
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os01t0871300-01(Os01g0871300)
OBR: 
BDI: 
SBI: 
SORBI_03g041180(SORBIDRAFT_03g041180) SORBI_09g021360(SORBIDRAFT_09g021360)
ZMA: 
100274472(pco075539) 100276531
SITA: 
ATR: 
s00010p00210410(AMTR_s00010p00210410)
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
MIS: 
MPP: 
BPG: 
CSL: 
CVR: 
PTI: 
TPS: 
PIF: 
 » show all
Taxonomy
Reference
1  [PMID:3985619]
  Authors
Bonner CA, Jensen RA.
  Title
Novel features of prephenate aminotransferase from cell cultures of Nicotiana silvestris.
  Journal
Arch. Biochem. Biophys. 238 (1985) 237-46.
  Organism
Nicotiana silvestris
Reference
2  [PMID:2939644]
  Authors
Siehl DL, Connelly JA, Conn EE.
  Title
Tyrosine biosynthesis in Sorghum bicolor: characteristics of prephenate aminotransferase.
  Journal
Z. Naturforsch. [C]. 41 (1986) 79-86.
  Organism
Sorghum bicolor
Reference
3  [PMID:3298985]
  Authors
Bonner C, Jensen R.
  Title
Prephenate aminotransferase.
  Journal
Methods. Enzymol. 142 (1987) 479-87.
  Organism
Corynebacterium glutamicum, Brevibacterium flavum, Nicotiana silvestris
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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