KEGG   ENZYME: 2.6.1.82Help
Entry
EC 2.6.1.82                 Enzyme                                 

Name
putrescine---2-oxoglutarate transaminase;
putrescine-alpha-ketoglutarate transaminase;
YgjG;
putrescine:alpha-ketoglutarate aminotransferase;
PAT;
putrescine transaminase (ambiguous);
putrescine aminotransferase (ambiguous);
butane-1,4-diamine:2-oxoglutarate aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
putrescine:2-oxoglutarate aminotransferase
Reaction(IUBMB)
putrescine + 2-oxoglutarate = 1-pyrroline + L-glutamate + H2O (overall reaction) [RN:R10064];
(1a) putrescine + 2-oxoglutarate = 4-aminobutanal + L-glutamate [RN:R01155];
(1b) 4-aminobutanal = 1-pyrroline + H2O (spontaneous) [RN:R07408]
Reaction(KEGG)
Substrate
putrescine [CPD:C00134];
2-oxoglutarate [CPD:C00026];
4-aminobutanal [CPD:C00555]
Product
1-pyrroline [CPD:C15668];
L-glutamate [CPD:C00025];
H2O [CPD:C00001];
4-aminobutanal [CPD:C00555]
Comment
A pyridoxal 5'-phosphate protein [3]. The product, 4-aminobutanal, spontaneously cyclizes to form 1-pyrroline, which is a substrate for EC 1.2.1.19, aminobutyraldehyde dehydrogenase. Cadaverine and spermidine can also act as substrates [3]. Forms part of the arginine-catabolism pathway [2]. cf. EC 2.6.1.113, putrescine---pyruvate transaminase.
History
EC 2.6.1.82 created 2006, modified 2017
Pathway
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Orthology
K09251  putrescine aminotransferase
Genes
ECO: b3073(patA)
ECJ: JW5510(ygjG)
ECD: ECDH10B_3248(ygjG)
EBW: BWG_2783(ygjG)
ECOK: ECMDS42_2542(ygjG)
ECE: Z4426(ygjG)
ECS: ECs3955
ECF: ECH74115_4387(ygjG)
ETW: ECSP_4047(ygjG)
ELX: CDCO157_3696
EOJ: ECO26_4174(ygjG)
EOI: ECO111_3895(ygjG)
EOH: ECO103_3818(ygjG)
ECG: E2348C_3366(ygjG)
EOK: G2583_3797(ygjG)
ECC: c3828(ygjG)
ECP: ECP_3163
ECI: UTI89_C3511(ygjG)
ECV: APECO1_3343(ygjG)
ECX: EcHS_A3255(ygjG)
ECW: EcE24377A_3540(rocD)
ECM: EcSMS35_3367(ygjG)
ECY: ECSE_3354
ECR: ECIAI1_3220(ygjG)
ECQ: ECED1_3741(ygjG)
ECK: EC55989_3487(ygjG)
ECT: ECIAI39_3571(ygjG)
EOC: CE10_3604(patA)
EUM: ECUMN_3556(ygjG)
ECZ: ECS88_3470(ygjG)
ELH: ETEC_3343
ESE: ECSF_2916
ESO: O3O_22055
ESM: O3M_03630
ESL: O3K_03590
EBR: ECB_02942(ygjG)
EBD: ECBD_0669
EKF: KO11_07355(ygjG)
EAB: ECABU_c34930(ygjG)
EDJ: ECDH1ME8569_2968(ygjG)
EIH: ECOK1_3505(rocD)
ENA: ECNA114_3166(ygjG)
EUN: UMNK88_3827(ygjG)
ELW: ECW_m3340(ygjG)
ELL: WFL_16320(ygjG)
ELC: i14_3520(ygjG)
ELD: i02_3520(ygjG)
ELP: P12B_c3190(ygjG)
EBL: ECD_02942(patA)
EBE: B21_02892(ygjG)
ELF: LF82_3225(ygjG)
ECOI: ECOPMV1_03391(patA)
ECOJ: P423_17360
ECOO: ECRM13514_4033(ygjG)
ECOH: ECRM13516_3836(ygjG)
ECOS: EC958_3479(ygjG)
EFE: EFER_3025(ygjG)
EAL: EAKF1_ch2857c(ygjG)
EMA: C1192_19755(ygjG)
STY: STY3396
STT: t3138
STM: STM3218(oat)
SEO: STM14_3896(oat)
SEY: SL1344_3191(oat)
SEJ: STMUK_3207(oat)
SEB: STM474_3372(oat)
SENI: CY43_16775
SPT: SPA3086(oat)
SEK: SSPA2882
SEI: SPC_3294(oat)
SEC: SCH_3165(oat)
SEH: SeHA_C3513(ygjG)
SHB: SU5_03713
SEE: SNSL254_A3479(ygjG)
SEW: SeSA_A3409(ygjG)
SEA: SeAg_B3405(ygjG)
SENS: Q786_15695
SED: SeD_A3575(rocD)
SEG: SG3114(oat)
SEL: SPUL_3231(oat)
SEGA: SPUCDC_3217(oat)
SET: SEN3060(oat)
SENA: AU38_15575
SENO: AU37_15775
SENV: AU39_15775
SENQ: AU40_17555
SENL: IY59_16180
SEEP: I137_15415
SENB: BN855_32980(ygjG)
SENE: IA1_15565
SBG: SBG_2853
SBZ: A464_3296
SFL: SF3114(ygjG)
SFX: S3320(ygjG)
SFV: SFV_3114(ygjG)
SFE: SFxv_3420(ygjG)
SFN: SFy_4444
SFS: SFyv_4521
SFT: NCTC1_03374(ygjG)
SSN: SSON_3211(ygjG)
SBO: SBO_2932(ygjG)
ENC: ECL_04458
ECLO: ENC_33220
EEC: EcWSU1_03889(patA)
ECLX: LI66_19490
ECLY: LI62_21450
ECLZ: LI64_18630
ESA: ESA_03492
CSK: ES15_3449
CTU: CTU_04740(patA)
KPN: KPN_03501(ygjG)
KPU: KP1_4798(ygjG)
KPP: A79E_0616
KPT: VK055_3967(ygjG)
KPE: KPK_0611(ygjG)
KPR: KPR_4705(patA)
KPJ: N559_0670
KPX: PMK1_01019(patA)
KPNU: LI86_03245
KPNK: BN49_0606(patA)
KVA: Kvar_0599
KOX: KOX_03220
KOE: A225_5093
EAE: EAE_03880
EAR: CCG33216
KQV: B8P98_03285(ygjG)
CKO: CKO_04486
CRO: ROD_48051
CWE: CO701_01070(ygjG)
CAMA: F384_24635
CAF: AL524_23390(ygjG)
CIF: AL515_20310(ygjG)
CFAR: CI104_03360(ygjG)
CIR: C2U53_06125(ygjG)
EBT: EBL_c04700(ygjG)
LEH: C3F35_15085(ygjG)
LNI: CWR52_15710(ygjG)
LEW: DAI21_07800(ygjG)
EBF: D782_0607
SERA: Ser39006_017225(ygjG)
RAA: Q7S_09650
ECA: ECA1543
PATR: EV46_07805
PATO: GZ59_15810
PEC: W5S_1732
SOD: Sant_1573
DDQ: DDI_1242
PFC: PflA506_2598(patA)
BGP: BGL_2c09700(argD) BGL_2c11910(patA)
DBA: Dbac_2006
DSF: UWK_00860
DOL: Dole_1070
CCX: COCOR_03198(argD)
BMR: BMI_II845
BTM: MC28_0591
BWW: bwei_3644(ygjG)
BMYC: DJ92_4003
BMYO: BG05_4537(ygjG)
BMQ: BMQ_0863(rocD)
BMD: BMD_0864(rocD)
BMH: BMWSH_4378(ygjG)
BMEG: BG04_3159
BAG: Bcoa_3317
GEA: GARCT_01452(patA_2)
PMS: KNP414_07440(patA2)
PMW: B2K_35280
ASOC: CB4_00046(patA_1)
BTS: Btus_0600
LLK: LLKF_1589
LLJ: LG36_0894
CBE: Cbei_4934
CBZ: Cbs_4934
CSR: Cspa_c29400(patA)
CACE: CACET_c35030(patA)
AMT: Amet_4317
AOE: Clos_2419
CCE: Ccel_1814
RUM: CK1_29070
CPRO: CPRO_14640(patA_3)
SLP: Slip_1325
DRM: Dred_2058
DAE: Dtox_1194
PTH: PTH_1726(ArgD)
DAU: Daud_0653
HMO: HM1_1941(oat)
SAY: TPY_1764(rocD) TPY_2989
CTHM: CFE_1259
TTE: TTE2339(ArgD)
THX: Thet_2097
TIT: Thit_2031
TKI: TKV_c21020(patA)
CHY: CHY_1436
MTA: Moth_1785
ADG: Adeg_1419
TPZ: Tph_c13270(argD1)
TOC: Toce_0940
TTM: Tthe_0388
TSH: Tsac_0964
PFT: JBW_01313
MAB: MAB_2279
MABB: MASS_2203
MABO: NF82_11395
MSTE: MSTE_02492
NCY: NOCYR_5148(patA)
SCO: SCO1284(2SCG18.31c)
SMA: SAVERM_2285(rocD3)
SGR: SGR_2290
SCT: SCAT_5590(patA)
SBH: SBI_01944
SHY: SHJG_0313
SVE: SVEN_4888
SALS: SLNWT_4936
STRE: GZL_09114
SAMB: SAM23877_1365(patA)
SRW: TUE45_02122(patA)
SLE: sle_03180(sle_03180)
MPH: MLP_04660
NML: Namu_5127
AMI: Amir_3615
ALL: CRK58238
ACTN: L083_2318
TRA: Trad_2914
TTH: TT_C0553
TTJ: TTHA0909
TSC: TSC_c09430(patA)
TAQ: TO73_0717
MRB: Mrub_1580
 » show all
Taxonomy
Reference
1  [PMID:3510672]
  Authors
Prieto-Santos MI, Martin-Checa J, Balana-Fouce R, Garrido-Pertierra A.
  Title
A pathway for putrescine catabolism in Escherichia coli.
  Journal
Biochim. Biophys. Acta. 880 (1986) 242-4.
Reference
2  [PMID:16023116]
  Authors
Samsonova NN, Smirnov SV, Novikova AE, Ptitsyn LR.
  Title
Identification of Escherichia coli K12 YdcW protein as a gamma-aminobutyraldehyde dehydrogenase.
  Journal
FEBS. Lett. 579 (2005) 4107-12.
Reference
3  [PMID:12617754]
  Authors
Samsonova NN, Smirnov SV, Altman IB, Ptitsyn LR.
  Title
Molecular cloning and characterization of Escherichia coli K12 ygjG gene.
  Journal
BMC. Microbiol. 3 (2003) 2.
  Sequence
[eco:b3073]
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.82
IUBMB Enzyme Nomenclature: 2.6.1.82
ExPASy - ENZYME nomenclature database: 2.6.1.82
BRENDA, the Enzyme Database: 2.6.1.82
CAS: 98982-73-1

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