KEGG   ENZYME: 2.6.1.99Help
Entry
EC 2.6.1.99                 Enzyme                                 

Name
L-tryptophan---pyruvate aminotransferase;
TAA1 (gene name);
vt2 (gene name)
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
L-tryptophan:pyruvate aminotransferase
Reaction(IUBMB)
L-tryptophan + pyruvate = indole-3-pyruvate + L-alanine [RN:R10180]
Reaction(KEGG)
Substrate
L-tryptophan [CPD:C00078];
pyruvate [CPD:C00022]
Product
indole-3-pyruvate [CPD:C00331];
L-alanine [CPD:C00041]
Comment
This plant enzyme, along with EC 1.14.13.168, indole-3-pyruvate monooxygenase, is responsible for the biosynthesis of the plant hormone indole-3-acetate from L-tryptophan.
History
EC 2.6.1.99 created 2012
Pathway
Tryptophan metabolism
Metabolic pathways
Orthology
K16903  
L-tryptophan---pyruvate aminotransferase
Genes
ATH: 
AT1G23320(TAR1) AT1G70560(TAA1) AT4G24670(TAR2)
ALY: 
CRB: 
CSAT: 
EUS: 
BRP: 
BNA: 
BOE: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
GHI: 
EGR: 
GMX: 
PVU: 
VRA: 
VAR: 
CCAJ: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj1g3v0318800.1(Lj1g3v0318800.1) Lj1g3v0318800.2(Lj1g3v0318800.2) Lj1g3v0329870.1(Lj1g3v0329870.1) Lj2g3v1415340.1(Lj2g3v1415340.1) Lj2g3v1415360.1(Lj2g3v1415360.1) Lj2g3v1415390.1(Lj2g3v1415390.1) Lj4g3v1451990.1(Lj4g3v1451990.1)
LANG: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
ZJU: 
CSV: 
CMO: 
MCHA: 
RCU: 
JCU: 
POP: 
POPTR_0010s05450g(POPTRDRAFT_769111) POPTR_0012s08520g(POPTRDRAFT_421831)
VVI: 
SLY: 
SPEN: 
SOT: 
CANN: 
NTA: 
NSY: 
NTO: 
INI: 
SIND: 
HAN: 
BVG: 
NNU: 
OSA: 
DOSA: 
Os01t0169800-01(Os01g0169800) Os05t0169300-01(Os05g0169300)
OBR: 
BDI: 
ATS: 
SBI: 
ZMA: 
SITA: 
PDA: 
EGU: 
MUS: 
DCT: 
ATR: 
SMO: 
PPP: 
 » show all
Taxonomy
Reference
1  [PMID:18394996]
  Authors
Tao Y, Ferrer JL, Ljung K, Pojer F, Hong F, Long JA, Li L, Moreno JE, Bowman ME, Ivans LJ, Cheng Y, Lim J, Zhao Y, Ballare CL, Sandberg G, Noel JP, Chory J
  Title
Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants.
  Journal
Cell. 133 (2008) 164-76.
  Sequence
Reference
2  [PMID:22025724]
  Authors
Mashiguchi K, Tanaka K, Sakai T, Sugawara S, Kawaide H, Natsume M, Hanada A, Yaeno T, Shirasu K, Yao H, McSteen P, Zhao Y, Hayashi K, Kamiya Y, Kasahara H
  Title
The main auxin biosynthesis pathway in Arabidopsis.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 108 (2011) 18512-7.
  Sequence
[ath:AT1G70560]
Reference
3  [PMID:21335375]
  Authors
Phillips KA, Skirpan AL, Liu X, Christensen A, Slewinski TL, Hudson C, Barazesh S, Cohen JD, Malcomber S, McSteen P
  Title
vanishing tassel2 encodes a grass-specific tryptophan aminotransferase required for vegetative and reproductive development in maize.
  Journal
Plant. Cell. 23 (2011) 550-66.
  Sequence
[zma:103634861]
Reference
4  [PMID:22155950]
  Authors
Zhao Y
  Title
Auxin biosynthesis: a simple two-step pathway converts tryptophan to indole-3-acetic acid in plants.
  Journal
Mol. Plant. 5 (2012) 334-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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