KEGG   ENZYME: 2.7.1.114Help
Entry
EC 2.7.1.114                Enzyme                                 

Name
AMP---thymidine kinase;
adenylate-nucleoside phosphotransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
AMP:thymidine 5'-phosphotransferase
Reaction(IUBMB)
AMP + thymidine = adenosine + dTMP [RN:R01571]
Reaction(KEGG)
Substrate
AMP [CPD:C00020];
thymidine [CPD:C00214]
Product
adenosine [CPD:C00212];
dTMP [CPD:C00364]
Comment
The deoxypyrimidine kinase complex induced by Herpes simplex virus catalyses this reaction as well as those of EC 2.7.1.21 (thymidine kinase), EC 2.7.1.118 (ADP---thymidine kinase) and EC 2.7.4.9 (dTMP kinase).
History
EC 2.7.1.114 created 1984
Reference
1  [PMID:6293576]
  Authors
Falke D, Labenz J, Brauer D, Muller WE.
  Title
Adenosine diphosphate: thymidine 5'-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase.
  Journal
Biochim. Biophys. Acta. 708 (1982) 99-103.
Reference
2  [PMID:6267178]
  Authors
Falke D, Nehrbass W, Brauer D, Muller WE.
  Title
Adenylic acid: deoxythymidine 5'-phosphotransferase: evidence for the existence of a novel herpes simplex virus-induced enzyme.
  Journal
J. Gen. Virol. 53 (1981) 247-55.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
60440-28-0

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