KEGG   ENZYME: 2.7.1.168Help
Entry
EC 2.7.1.168                Enzyme                                 

Name
D-glycero-alpha-D-manno-heptose-7-phosphate kinase;
D-alpha-D-heptose-7-phosphate kinase;
hdda (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:D-glycero-alpha-D-manno-heptose 7-phosphate 1-phosphotransferase
Reaction(IUBMB)
D-glycero-alpha-D-manno-heptose 7-phosphate + ATP = D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + ADP [RN:R09770]
Reaction(KEGG)
Substrate
D-glycero-alpha-D-manno-heptose 7-phosphate [CPD:C19878];
ATP [CPD:C00002]
Product
D-glycero-alpha-D-manno-heptose 1,7-bisphosphate [CPD:C19879];
ADP [CPD:C00008]
Comment
The enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose, which is required for assembly of S-layer glycoprotein in Gram-positive bacteria. The enzyme is specific for the alpha-anomer.
History
EC 2.7.1.168 created 2010
Pathway
Lipopolysaccharide biosynthesis
Orthology
K07031  
D-glycero-alpha-D-manno-heptose-7-phosphate kinase
Genes
YPB: 
PLU: 
plu4822(wblW)
PPB: 
PEN: 
SBB: 
AMAG: 
TVI: 
HCH: 
TOL: 
TOR: 
REU: 
BMA: 
BMA2296(hddA)
BMV: 
BML: 
BMN: 
BPS: 
BPSL2796(wcbL)
BPM: 
BPL: 
BPD: 
BPR: 
BPSE: 
BPSU: 
BPZ: 
BPQ: 
BPK: 
BTD: 
HSE: 
NET: 
MEH: 
CJE: 
Cj1425c(hddA)
CJB: 
CJJ: 
CJN: 
CJS: 
CJEJ: 
CJEU: 
CJEN: 
CJEI: 
CJR: 
CJD: 
CJZ: 
CJX: 
ANT: 
GLO: 
DMA: 
DAS: 
DPI: 
LIP: 
LIA008(mvaK1) LIC011(mvaK1)
LIR: 
BBA: 
Bd1027(lmbP)
BBAT: 
Bdt_0972(lmbP)
BBW: 
BBAC: 
BEX: 
BMX: 
DOL: 
DAL: 
DAT: 
DTO: 
SCL: 
SCU: 
DTI: 
HMR: 
SFD: 
RLT: 
RLB: 
BJA: 
MRD: 
CAK: 
CSE: 
AEX: 
JAN: 
KVU: 
KVL: 
KVU_0341(lmbP)
SCH: 
MAG: 
MGY: 
AZL: 
ALI: 
MGM: 
APB: 
BSUB: 
LLK: 
LLM: 
LLR: 
LLN: 
LLW: 
EFAU: 
CAC: 
CAE: 
CAY: 
FPA: 
RHO: 
RTO: 
CSH: 
CSO: 
SGY: 
DMI: 
DEC: 
HMO: 
BPRM: 
BPRS: 
SRI: 
MTU: 
Rv0115(hddA)
MTV: 
MTC: 
MRA: 
MRA_0121(hddA)
MTF: 
MTB: 
MTK: 
MTZ: 
MTG: 
MTI: 
MTE: 
MTUR: 
CFBS_0124(hddA)
MTL: 
MTO: 
MTD: 
UDA_0115(hddA)
MTN: 
MTJ: 
MTUB: 
MTUC: 
MTUE: 
MTUH: 
MTUL: 
MBO: 
MBB: 
MBT: 
MBM: 
MBK: 
MCE: 
MCQ: 
MCV: 
MCX: 
MCZ: 
MPA: 
MAO: 
MAV: 
MIT: 
MIR: 
MIA: 
MID: 
MYO: 
MMM: 
CFL: 
CWO: 
EYY: 
SNG: 
OTE: 
TAZ: 
TPI: 
ABA: 
ACA: 
SUS: 
CTM: 
GAU: 
GBA: 
AMO: 
SYN: 
slr0862(lmbP)
SYZ: 
SYY: 
SYT: 
SYS: 
SYQ: 
MAR: 
CYT: 
cce_0966(lmbP)
CYP: 
CYH: 
CAN: 
CYU: 
PMI: 
PMH: 
BTH: 
BFG: 
CPI: 
NKO: 
OHO: 
PAA: 
DET: 
DEB: 
DMD: 
RRS: 
RCA: 
CAU: 
CAG: 
CHL: 
HAU: 
ATM: 
CAP: 
TRA: 
MSV: 
MHD: 
MPZ: 
CCZ: 
NDE: 
LFI: 
TTR: 
MOX: 
MPI: 
MER: 
MEL: 
MAX: 
TAC: 
TVO: 
PTO: 
FAC: 
TAR: 
NKR: 
 » show all
Taxonomy
Reference
1  [PMID:11279237]
  Authors
Kneidinger B, Graninger M, Puchberger M, Kosma P, Messner P
  Title
Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose.
  Journal
J. Biol. Chem. 276 (2001) 20935-44.
  Organism
Aneurinibacillus thermoaerophilus
  Sequence
[up:Q9AGY8]
Reference
2  [PMID:12101286]
  Authors
Valvano MA, Messner P, Kosma P
  Title
Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides.
  Journal
Microbiology. 148 (2002) 1979-89.
  Organism
Aneurinibacillus thermoaerophilus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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