KEGG   ENZYME: 2.7.1.179Help
Entry
EC 2.7.1.179                Enzyme                                 

Name
kanosamine kinase;
rifN (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:kanosamine 6-phosphotransferase
Reaction(IUBMB)
ATP + kanosamine = ADP + kanosamine 6-phosphate [RN:R06588]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
kanosamine [CPD:C12212]
Product
ADP [CPD:C00008];
kanosamine 6-phosphate [CPD:C12213]
Comment
The enzyme from the bacterium Amycolatopsis mediterranei is specific for kanosamine.
History
EC 2.7.1.179 created 2013
Pathway
Biosynthesis of ansamycins
Biosynthesis of antibiotics
Orthology
K16018  
kanosamine 6-kinase
Genes
SVL: 
FRA: 
FRE: 
FAL: 
SEN: 
SACE_2869(rifN)
AMD: 
AMED_0630(rifN)
AMN: 
AMM: 
AMES_0628(rifN)
AMZ: 
B737_0629(rifN)
AMI: 
SAQ: 
MAU: 
MIL: 
ACTN: 
 » show all
Taxonomy
Reference
1  [PMID:12207505]
  Authors
Arakawa K, Muller R, Mahmud T, Yu TW, Floss HG.
  Title
Characterization of the early stage aminoshikimate pathway in the formation of 3-amino-5-hydroxybenzoic acid: the RifN protein specifically converts kanosamine into kanosamine 6-phosphate.
  Journal
J. Am. Chem. Soc. 124 (2002) 10644-5.
  Sequence
[amn:RAM_03220]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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