KEGG   ENZYME: 2.7.1.186Help
Entry
EC 2.7.1.186                Enzyme                                 

Name
mevalonate-3-phosphate 5-kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:(R)-3-phosphomevalonate 5-phosphotransferase
Reaction(IUBMB)
ATP + (R)-3-phosphomevalonate = ADP + (R)-3,5-bisphosphomevalonate [RN:R10780]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
(R)-3-phosphomevalonate [CPD:C20847]
Product
ADP [CPD:C00008];
(R)-3,5-bisphosphomevalonate [CPD:C20848]
Comment
Mevalonate 3-kinase (EC 2.7.1.185) and mevalonate-3-phosphate-5-kinase act sequentially in an alternate mevalonate pathway in the archaeon Thermoplasma acidophilum.
History
EC 2.7.1.186 created 2014
Pathway
Terpenoid backbone biosynthesis
Orthology
K18690  
mevalonate-3-phosphate-5-kinase
Genes
TAC: 
PTO: 
FAC: 
Taxonomy
Reference
1  [PMID:24914732]
  Authors
Vinokur JM, Korman TP, Cao Z, Bowie JU.
  Title
Evidence of a novel mevalonate pathway in archaea.
  Journal
Biochemistry. 53 (2014) 4161-8.
  Sequence
[tac:Ta0762]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

DBGET integrated database retrieval system