KEGG   ENZYME: 2.7.1.209Help
Entry
EC 2.7.1.209                Enzyme                                 

Name
L-erythrulose 1-kinase;
lerK (gene name);
L-erythrulose 1-kinase [incorrect]
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:L-erythrulose 1-phosphotransferase
Reaction(IUBMB)
ATP + L-erythrulose = ADP + L-erythrulose 1-phosphate [RN:R11460]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
L-erythrulose [CPD:C02045]
Product
ADP [CPD:C00008];
L-erythrulose 1-phosphate [CPD:C03394]
Comment
The enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of L-threitol.
History
EC 2.7.1.209 created 2016, modified 2018
Orthology
K20901  L-erythrulose 1-kinase
Genes
MSM: MSMEG_6788
MSG: MSMEI_6605
MSB: LJ00_33540
MSN: LI99_33545
MSH: LI98_33550
MGO: AFA91_05905
MPHL: MPHLCCUG_03582(dhaK_2)
MLL: B1R94_28270
BCV: Bcav_1547
BFA: Bfae_00540
PFR: PFREUD_22470(dhaK_dhaL)
PFRE: RM25_2127
TPYO: X956_09105
 » show all
Taxonomy
Reference
1  [PMID:26560079]
  Authors
Huang H, Carter MS, Vetting MW, Al-Obaidi N, Patskovsky Y, Almo SC, Gerlt JA
  Title
A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis.
  Journal
J. Am. Chem. Soc. 137 (2015) 14570-3.
  Sequence
Reference
2  [PMID:26978037]
  Authors
Huang H, Carter MS, Vetting MW, Al-Obaidi N, Patskovsky Y, Almo SC, Gerlt JA.
  Title
Correction to "A General Strategy for the Discovery of Metabolic Pathways: D-Threitol, L-Threitol, and Erythritol Utilization in Mycobacterium smegmatis".
  Journal
J. Am. Chem. Soc. 138 (2016) 4267.
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.209
IUBMB Enzyme Nomenclature: 2.7.1.209
ExPASy - ENZYME nomenclature database: 2.7.1.209
BRENDA, the Enzyme Database: 2.7.1.209

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