KEGG   ENZYME: 2.7.1.214Help
Entry
EC 2.7.1.214                Enzyme                                 

Name
C7-cyclitol 7-kinase;
valC (gene name);
vldC (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:C7-cyclitol 7-phosphotransferase
Reaction(IUBMB)
(1) ATP + valienone = ADP + valienone 7-phosphate [RN:R11234];
(2) ATP + validone = ADP + validone 7-phosphate [RN:R11406]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
valienone [CPD:C17696];
validone [CPD:C21371]
Product
ADP [CPD:C00008];
valienone 7-phosphate [CPD:C17697];
validone 7-phosphate [CPD:C21218]
Comment
The enzyme, characterized from the bacterium Streptomyces hygroscopicus var. jinggangensis, is involved in the biosynthesis of the antifungal agent validamycin A.
History
EC 2.7.1.214 created 2016
Pathway
Acarbose and validamycin biosynthesis
Biosynthesis of antibiotics
Orthology
K20433  
C7-cyclitol 7-kinase
Genes
CJA: 
SUR: 
SHY: 
SHO: 
SGU: 
Taxonomy
Reference
1  [PMID:17335096]
  Authors
Minagawa K, Zhang Y, Ito T, Bai L, Deng Z, Mahmud T.
  Title
ValC, a new type of C7-Cyclitol kinase involved in the biosynthesis of the antifungal agent validamycin A.
  Journal
Chembiochem. 8 (2007) 632-41.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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