KEGG   ENZYME: 2.7.1.215Help
Entry
EC 2.7.1.215                Enzyme                                 

Name
erythritol kinase (D-erythritol 1-phosphate-forming);
eryA (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:erythritol 1-phosphotransferase
Reaction(IUBMB)
ATP + erythritol = ADP + D-erythritol 1-phosphate [RN:R11536]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
erythritol [CPD:C00503]
Product
ADP [CPD:C00008];
D-erythritol 1-phosphate [CPD:C21294]
Comment
The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism. cf. EC 2.7.1.27, erythritol kinase (D-erythritol 4-phosphate-forming).
History
EC 2.7.1.215 created 2016
Orthology
K00862  erythritol kinase (D-erythritol 1-phosphate-forming)
Genes
EFE: EFER_0338(eryA)
KLN: LH22_12790
PANT: PSNIH1_13465
SPIU: SPICUR_04390
HHU: AR456_16140
ZDF: AN401_07995
BUL: BW21_6384
BUD: AQ610_18890
VEI: Veis_2016
MLO: mlr7268
SME: SMc01623(eriA)
SMX: SM11_chr1024(eryA)
SMI: BN406_02059(eriA)
SMEL: SM2011_c01623(eryA)
SMER: DU99_12530
SMD: Smed_2159
SFD: USDA257_c12970(xylB1)
SAME: SAMCFNEI73_pC1169(eryA)
EAD: OV14_3647
ARA: Arad_7460(lyxX)
RLE: pRL120204(eryA)
RLG: Rleg_5323
SHZ: shn_16425
BME: BMEII0430
BMEL: DK63_2809
BMEE: DK62_2589
BMF: BAB2_0372(eryA)
BMB: BruAb2_0368(eryA)
BABO: DK55_2362
BABR: DO74_2782
BABT: DK49_2870
BABB: DK48_2329
BABU: DK53_2372
BABS: DK51_2951
BABC: DO78_2688
BMS: BRA0864(eryA)
BSI: BS1330_II0857(eryA)
BSF: BSS2_II0819(eryA)
BSZ: DK67_2818
BSV: BSVBI22_B0856(eryA)
BOL: BCOUA_II0864(eryA)
BCAR: DK60_2555
BCAS: DA85_14605
BMR: BMI_II858(eryA)
BPP: BPI_II920(eryA)
BPV: DK65_2785
BCET: V910_200428(eryA)
OAN: Oant_2911
OAH: DR92_3594
OCH: CES85_5819(eryA)
BRA: BRADO4795
BBT: BBta_3230
AOL: S58_28790
BRO: BRAD285_2448(eryA)
MMED: Mame_00678(eryA)
RDE: RD1_3634
PDE: Pden_4595
SPSE: SULPSESMR1_04461(eryA)
ACR: Acry_2571
SRW: TUE45_03247(eryA_10)
CACN: RN83_00270
SEN: SACE_5218(eryA) SACE_6531(eryA)
AMQ: AMETH_6522(eryA)
CAP: CLDAP_24770(xylB)
 » show all
Taxonomy
Reference
1  [PMID:163226]
  Authors
Sperry JF, Robertson DC
  Title
Erythritol catabolism by Brucella abortus.
  Journal
J. Bacteriol. 121 (1975) 619-30.
Reference
2  [PMID:12639570]
  Authors
Lillo AM, Tetzlaff CN, Sangari FJ, Cane DE
  Title
Functional expression and characterization of EryA, the erythritol kinase of Brucella abortus, and enzymatic synthesis of L-erythritol-4-phosphate.
  Journal
Bioorg. Med. Chem. Lett. 13 (2003) 737-9.
  Sequence
[bmf:BAB2_0372]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.215
IUBMB Enzyme Nomenclature: 2.7.1.215
ExPASy - ENZYME nomenclature database: 2.7.1.215
BRENDA, the Enzyme Database: 2.7.1.215

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