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Entry
EC 2.7.1.215                Enzyme                                 

Name
erythritol kinase (D-erythritol 1-phosphate-forming);
eryA (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:erythritol 1-phosphotransferase
Reaction(IUBMB)
ATP + erythritol = ADP + D-erythritol 1-phosphate [RN:R11536]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
erythritol [CPD:C00503]
Product
ADP [CPD:C00008];
D-erythritol 1-phosphate [CPD:C21294]
Comment
The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism. cf. EC 2.7.1.27, erythritol kinase (D-erythritol 4-phosphate-forming).
History
EC 2.7.1.215 created 2016
Orthology
K00862  
erythritol kinase (D-erythritol 1-phosphate-forming)
Genes
EFE: 
EFER_0338(eryA)
KLN: 
PANT: 
SPIU: 
HHU: 
ZDF: 
BUL: 
BUD: 
VEI: 
MLO: 
MLN: 
MCI: 
MOP: 
MAM: 
MAMO: 
MESW: 
SME: 
SMc01623(eriA)
SMK: 
SMQ: 
SMX: 
SMI: 
SMEG: 
SMEL: 
SMER: 
SMD: 
RHI: 
SFH: 
SFD: 
SIX: 
SAME: 
SINO: 
EAD: 
EAH: 
ARA: 
Arad_7460(lyxX)
RLE: 
pRL120204(eryA)
RLG: 
RLB: 
RTR: 
RGA: 
SHZ: 
BME: 
BMEL: 
BMI: 
BMZ: 
BMG: 
BMW: 
BMEE: 
BMF: 
BAB2_0372(eryA)
BMB: 
BMC: 
BAA: 
BABO: 
BABR: 
BABT: 
BABB: 
BABU: 
BABS: 
BABC: 
BMS: 
BRA0864(eryA)
BSI: 
BSF: 
BSUI: 
BSUP: 
BSUV: 
BSUC: 
BMT: 
BSZ: 
BSV: 
BSW: 
BSG: 
BSK: 
BOL: 
BCAR: 
BCAS: 
BMR: 
BMI_II858(eryA)
BPP: 
BPI_II920(eryA)
BPV: 
BCET: 
BVL: 
OAN: 
OAH: 
OPS: 
OCH: 
BRA: 
BBT: 
AOL: 
BRO: 
MMED: 
AUA: 
RSK: 
RDE: 
RLI: 
PDE: 
OAR: 
CMAR: 
MALG: 
LAGG: 
SPSE: 
DON: 
TPRO: 
THW: 
ACR: 
AMV: 
KBA: 
NCH: 
SRW: 
TUE45_03247(eryA_10)
SGS: 
CACN: 
SEN: 
SACE_5218(eryA) SACE_6531(eryA)
AMQ: 
AEY: 
CAP: 
 » show all
Taxonomy
Reference
1  [PMID:163226]
  Authors
Sperry JF, Robertson DC
  Title
Erythritol catabolism by Brucella abortus.
  Journal
J. Bacteriol. 121 (1975) 619-30.
Reference
2  [PMID:12639570]
  Authors
Lillo AM, Tetzlaff CN, Sangari FJ, Cane DE
  Title
Functional expression and characterization of EryA, the erythritol kinase of Brucella abortus, and enzymatic synthesis of L-erythritol-4-phosphate.
  Journal
Bioorg. Med. Chem. Lett. 13 (2003) 737-9.
  Sequence
[bmf:BAB2_0372]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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