KEGG   ENZYME: 2.7.1.65Help
Entry
EC 2.7.1.65                 Enzyme                                 

Name
scyllo-inosamine 4-kinase;
scyllo-inosamine kinase (phosphorylating);
scyllo-inosamine kinase;
ATP:inosamine phosphotransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase
Reaction(IUBMB)
ATP + 1-amino-1-deoxy-scyllo-inositol = ADP + 1-amino-1-deoxy-scyllo-inositol 4-phosphate [RN:R03384]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
1-amino-1-deoxy-scyllo-inositol [CPD:C01214]
Product
ADP [CPD:C00008];
1-amino-1-deoxy-scyllo-inositol 4-phosphate [CPD:C01283]
Comment
Also acts on streptamine, 2-deoxystreptamine and 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol.
History
EC 2.7.1.65 created 1972, modified 1976
Pathway
Streptomycin biosynthesis
Biosynthesis of secondary metabolites
Orthology
K04339  
scyllo-inosamine 4-kinase
Genes
SGR: 
SGR_5919(stsE)
Taxonomy
Reference
1  [PMID:4376579]
  Authors
Walker JB.
  Title
Enzymatic reactions involved in streptomycin biosynthesis and metabolism.
  Journal
Lloydia. 34 (1971) 363-71.
  Organism
Streptomyces griseus, Streptomyces bikiniensis
Reference
2  [PMID:6076630]
  Authors
Walker JB, Walker MS.
  Title
Enzymatic synthesis of streptidine from scyllo-inosamine.
  Journal
Biochemistry. 6 (1967) 3821-9.
  Organism
Streptomyces griseus, Streptomyces bikiniensis
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37278-08-3

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