KEGG   ENZYME: 2.7.1.8Help
Entry
EC 2.7.1.8                  Enzyme                                 

Name
glucosamine kinase;
glucosamine kinase (phosphorylating);
ATP:2-amino-2-deoxy-D-glucose-6-phosphotransferase;
aminodeoxyglucose kinase;
ATP:D-glucosamine phosphotransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:D-glucosamine 6-phosphotransferase
Reaction(IUBMB)
ATP + D-glucosamine = ADP + D-glucosamine 6-phosphate [RN:R01961]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
D-glucosamine [CPD:C00329]
Product
ADP [CPD:C00008];
D-glucosamine 6-phosphate [CPD:C00352]
Comment
The enzyme has been studied in the bacterium Vibrio cholerae, where it participates in a chitin degradation pathway.
History
EC 2.7.1.8 created 1961, modified 2014
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
ec01100  Metabolic pathways
Orthology
K18676  glucosamine kinase
Genes
CED: LH89_09620 LH89_16355
KOR: AWR26_20120
KRD: A3780_03730
SERA: Ser39006_008770
ECA: ECA3753
PATR: EV46_18400
PATO: GZ59_37500
PCT: PC1_3528
PCC: PCC21_035220
PCV: BCS7_17695
PEC: W5S_3817
EBI: EbC_09180
PAM: PANA_0315
PAJ: PAJ_3476
PVA: Pvag_3579
PSTW: DSJ_03620
VCH: VC0614
VCI: O3Y_02860
VCS: MS6_0432
VVU: VV1_1667
VVY: VV2740
VPA: VP2485
VPB: VPBB_2311
VAG: N646_1582
VSP: VS_2512
VAN: VAA_00774
VSC: VSVS12_00703(gspK)
VFI: VF_2145
PPR: PBPRA0519(R00200)
SON: SO_3507(nagK)
SDN: Sden_2706
SAZ: Sama_0944
SBL: Sbal_1084
SLO: Shew_1116
SSE: Ssed_1212
SPL: Spea_1101
SHL: Shal_1149
SWD: Swoo_1312
SWP: swp_3703
SVO: SVI_1023
SPSW: Sps_02363
CPS: CPS_1026
PAT: Patl_0124
PSM: PSM_B0132
PSEO: OM33_11650
PSPO: PSPO_a1857
PTU: PTUN_a1747(gspK)
AMAL: I607_14150
AMAO: I634_14390
AMAI: I635_14820
AMAG: I533_13975
GNI: GNIT_0638
FBL: Fbal_2921
CJA: CJA_1160
SDE: Sde_3036
MICC: AUP74_00061(gspK_1) AUP74_02805(gspK_3)
GAI: IMCC3135_01345(gspK_1)
HCH: HCH_06985
AHA: AHA_3099
ASA: ASA_3106
AVR: B565_1043
AMED: B224_1114
ASR: WL1483_83(gspK)
CVI: CV_2896
BMA: BMA2870
BMAL: DM55_909
BMAE: DM78_812
BMAQ: DM76_886
BMAI: DM57_1623
BMAF: DM51_2487
BMAZ: BM44_255
BMAB: BM45_3033
BPS: BPSL3316
BPSE: BDL_2059
BPSM: BBQ_3517
BPSU: BBN_103
BPSD: BBX_451
BPK: BBK_1548
BPSH: DR55_1185
BPSA: BBU_2223
BPSO: X996_798
BUT: X994_2817
BTE: BTH_I3192
BTQ: BTQ_3132
BTJ: BTJ_2562
BTZ: BTL_474
BTD: BTI_240
BTV: BTHA_567
BTHE: BTN_884
BTHM: BTRA_681
BTHA: DR62_1080
BTHL: BG87_691
BOK: DM82_3019
BOC: BG90_1696
BVE: AK36_595
BCN: Bcen_2861
BCJ: BCAL0119
BCEN: DM39_53
BCEW: DM40_949
BCEO: I35_0126
BAM: Bamb_0159
BMU: Bmul_0155
BMJ: BMULJ_03109(nagK)
BMK: DM80_1532
BMUL: NP80_288
BCT: GEM_0151
BCED: DM42_1582
BDL: AK34_2908
BCON: NL30_18650
BUB: BW23_1511
BLAT: WK25_01505
BTEI: WS51_11630
BSEM: WJ12_00885
BPSL: WS57_13775
BMEC: WJ16_00840
BSTG: WT74_01150
BGU: KS03_1089
BGO: BM43_1583
BUK: MYA_0168
BUL: BW21_324
BXE: Bxe_A0107
BXB: DR64_2282
BPH: Bphy_2984
BFN: OI25_1597
RTA: Rta_30025
JAG: GJA_4144
HSE: Hsero_4554(nagK)
CFU: CFU_2609(nagK2) CFU_2985(nagK1)
CPRA: CPter91_1545(nagK1) CPter91_3368(nagK2)
LCH: Lcho_4217
PBH: AAW51_4933(gspK)
MES: Meso_2705
SME: SMc02875
SMER: DU99_01025
SMD: Smed_3407
SIX: BSY16_656
EAD: OV14_1045
RLE: RL3360
RLG: Rleg_2907
RHL: LPU83_2787(NAGK)
RHT: NT26_4005
SHZ: shn_11305
BMR: BMI_II509
RVA: Rvan_3458
PHL: KKY_2
HDI: HDIA_2827(gspK)
SIL: SPO1841
JAN: Jann_1358
RDE: RD1_1728
PDE: Pden_2474
PSF: PSE_4341
PGD: Gal_00635
OTM: OSB_04490(gspK)
MALG: MALG_04280
AHT: ANTHELSMS3_01829(gspK)
ZMO: ZMO1169
ZMN: Za10_0159
ZMM: Zmob_0160
ZMB: ZZ6_0162
ZMI: ZCP4_0164
GDI: GDI3226
GDJ: Gdia_3136
TXI: TH3_09625
GBA: J421_3609
 » show all
Taxonomy
Reference
1  [PMID:13242546]
  Authors
BUEDING E, MACKINNON JA.
  Title
Hexokinases of Schistosoma mansoni.
  Journal
J. Biol. Chem. 215 (1955) 495-506.
Reference
2  [PMID:11850417]
  Authors
Park JK, Wang LX, Roseman S
  Title
Isolation of a glucosamine-specific kinase, a unique enzyme of Vibrio cholerae.
  Journal
J. Biol. Chem. 277 (2002) 15573-8.
  Sequence
[vch:VC0614]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.8
IUBMB Enzyme Nomenclature: 2.7.1.8
ExPASy - ENZYME nomenclature database: 2.7.1.8
BRENDA, the Enzyme Database: 2.7.1.8
CAS: 9031-90-7

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