KEGG   ENZYME: 2.7.1.81Help
Entry
EC 2.7.1.81                 Enzyme                                 

Name
hydroxylysine kinase;
hydroxylysine kinase (phosphorylating);
guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
GTP:5-hydroxy-L-lysine O-phosphotransferase
Reaction(IUBMB)
GTP + 5-hydroxy-L-lysine = GDP + 5-phosphonooxy-L-lysine [RN:R03378]
Reaction(KEGG)
Substrate
GTP [CPD:C00044];
5-hydroxy-L-lysine [CPD:C16741]
Product
GDP [CPD:C00035];
5-phosphonooxy-L-lysine [CPD:C03366]
Comment
Both the natural 5-hydroxy-L-lysine and its 5-epimer act as acceptors.
History
EC 2.7.1.81 created 1972
Pathway
Lysine degradation
Metabolic pathways
Orthology
K18201  
hydroxylysine kinase
Genes
HSA: 
123688(HYKK)
PTR: 
739839(AGPHD1)
PPS: 
100990244(AGPHD1)
GGO: 
101138799(AGPHD1)
PON: 
100455708(AGPHD1)
MCC: 
710329(AGPHD1)
MCF: 
102143817(HYKK)
MMU: 
235386(Hykk)
RNO: 
300723(Hykk)
CGE: 
100756410(Hykk)
HGL: 
101702212(Hykk)
TUP: 
102477505(HYKK)
CFA: 
475133(HYKK)
AML: 
FCA: 
101085212(HYKK)
PTG: 
102965109(HYKK)
BTA: 
530270(HYKK)
BOM: 
102281469(HYKK)
PHD: 
102316903(HYKK)
CHX: 
102183458(HYKK)
OAS: 
101122555(AGPHD1)
SSC: 
100155220(AGPHD1)
CFR: 
102517400(HYKK)
BACU: 
103015933(HYKK)
LVE: 
ECB: 
100060343(HYKK)
MYB: 
102242468(HYKK)
MYD: 
102754822(HYKK)
PALE: 
102877942(HYKK)
MDO: 
100025929(HYKK)
SHR: 
100925038(AGPHD1)
OAA: 
100082548(HYKK)
GGA: 
415358(AGPHD1)
TGU: 
100225104(AGPHD1)
FAB: 
101812642(HYKK)
PHI: 
102101087(HYKK)
APLA: 
101794962(HYKK)
FPG: 
101924119(HYKK)
FCH: 
102057217(HYKK)
CLV: 
102084439(HYKK)
ASN: 
102385118(HYKK)
AMJ: 
102577359(HYKK)
PSS: 
102449467(HYKK)
CMY: 
102929726(HYKK)
PBI: 
103058107(HYKK)
XLA: 
398833(hykk)
XTR: 
549168(hykk)
DRE: 
559560(hykk.2) 559635(hykk.1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
DAN: 
DSE: 
DWI: 
DGR: 
DMO: 
DVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
BPG: 
MIS: 
MPP: 
DFA: 
ACAN: 
NGD: 
EHX: 
GTT: 
 » show all
Taxonomy
Reference
1  [PMID:4621658]
  Authors
Hiles RA, Henderson LM.
  Title
The partial purification and properties of hydroxylysine kinase from rat liver.
  Journal
J. Biol. Chem. 247 (1972) 646-51.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9073-58-9

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