KEGG   ENZYME: 2.7.1.86Help
Entry
EC 2.7.1.86                 Enzyme                                 

Name
NADH kinase;
reduced nicotinamide adenine dinucleotide kinase (phosphorylating);
DPNH kinase;
reduced diphosphopyridine nucleotide kinase;
NADH kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:NADH 2'-phosphotransferase
Reaction(IUBMB)
ATP + NADH = ADP + NADPH [RN:R00105]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
NADH [CPD:C00004]
Product
ADP [CPD:C00008];
NADPH [CPD:C00005]
Comment
CTP, ITP, UTP and GTP can also act as phosphate donors (in decreasing order of activity). The enzyme is specific for NADH. Activated by acetate.
History
EC 2.7.1.86 created 1976 (EC 2.7.1.96 created 1978, incorporated 1978)
Reference
1  [PMID:4335000]
  Authors
Griffiths MM, Bernofsky C.
  Title
Purification and properties of reduced diphosphopyridine nucleotide kinase from yeast mitochondria.
  Journal
J. Biol. Chem. 247 (1972) 1473-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
62213-39-2

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