KEGG   ENZYME: 2.7.11.32Help
Entry
EC 2.7.11.32                Enzyme                                 

Name
[pyruvate, phosphate dikinase] kinase;
PPDK regulatory protein (ambiguous);
pyruvate;
phosphate dikinase regulatory protein (ambiguous);
bifunctional dikinase regulatory protein (ambiguous)
Class
Transferases;
Transferring phosphorus-containing groups;
Protein-serine/threonine kinases
BRITE hierarchy
Sysname
ADP:[pyruvate, phosphate dikinase] phosphotransferase
Reaction(IUBMB)
ADP + [pyruvate, phosphate dikinase] = AMP + [pyruvate, phosphate dikinase] phosphate
Substrate
ADP [CPD:C00008];
[pyruvate, phosphate dikinase]
Product
AMP [CPD:C00020];
[pyruvate, phosphate dikinase] phosphate
Comment
The enzymes from the plants Zea mays (maize) and Arabidopsis thaliana are bifunctional and catalyse both the phosphorylation and dephosphorylation of EC 2.7.9.1 (pyruvate, phosphate dikinase). cf. EC 2.7.4.27, [pyruvate, phosphate dikinase]-phosphate phosphotransferase [2-5]. The enzyme is specific for a reaction intermediate form of EC 2.7.9.1, and phosphorylates a threonine located adjacent to the catalytic histidine. The phosphorylation only takes place if the histidine is already phosphorylated [3-5].
History
EC 2.7.11.32 created 2012
Orthology
K20115  
[pyruvate, phosphate dikinase]-phosphate phosphotransferase / [pyruvate, phosphate dikinase] kinase
Genes
ATH: 
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
VAR: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj5g3v2060750.1(Lj5g3v2060750.1)
LANG: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
VVI: 
SLY: 
SPEN: 
SOT: 
INI: 
SIND: 
BVG: 
NNU: 
OSA: 
4343450(BFRP)
DOSA: 
Os07t0530600-01(Os07g0530600)
OBR: 
BDI: 
ATS: 
SBI: 
SORBI_02g035190(SORBIDRAFT_02g035190) SORBI_02g035210(SORBIDRAFT_02g035210)
ZMA: 
100279565(GRMZM2G004880) 732785(pco142971)
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
MIS: 
MPP: 
SMIN: 
v1.2.014430.t1(symbB.v1.2.014430.t1) v1.2.022569.t1(symbB.v1.2.022569.t1) v1.2.027162.t1(symbB.v1.2.027162.t1) v1.2.028672.t1(symbB.v1.2.028672.t1) v1.2.040824.t3(symbB.v1.2.040824.t3)
PTI: 
GTT: 
 » show all
Taxonomy
Reference
1  [PMID:6326674]
  Authors
Burnell JN, Hatch MD
  Title
Regulation of C4 photosynthesis: identification of a catalytically important histidine residue and its role in the regulation of pyruvate,Pi dikinase.
  Journal
Arch. Biochem. Biophys. 231 (1984) 175-82.
  Sequence
[zma:732785]
Reference
2  [PMID:2983615]
  Authors
Burnell JN, Hatch MD
  Title
Regulation of C4 photosynthesis: purification and properties of the protein catalyzing ADP-mediated inactivation and Pi-mediated activation of pyruvate,Pi dikinase.
  Journal
Arch. Biochem. Biophys. 237 (1985) 490-503.
  Sequence
[zma:732785]
Reference
3  [PMID:10683263]
  Authors
Chastain CJ, Botschner M, Harrington GE, Thompson BJ, Mills SE, Sarath G, Chollet R
  Title
Further analysis of maize C(4) pyruvate,orthophosphate dikinase phosphorylation by its bifunctional regulatory protein using selective substitutions of the regulatory Thr-456 and catalytic His-458 residues.
  Journal
Arch. Biochem. Biophys. 375 (2000) 165-70.
  Sequence
[zma:732785]
Reference
4  [PMID:16696949]
  Authors
Burnell JN, Chastain CJ
  Title
Cloning and expression of maize-leaf pyruvate, Pi dikinase regulatory protein gene.
  Journal
Biochem. Biophys. Res. Commun. 345 (2006) 675-80.
  Sequence
[zma:732785]
Reference
5  [PMID:17996018]
  Authors
Chastain CJ, Xu W, Parsley K, Sarath G, Hibberd JM, Chollet R
  Title
The pyruvate, orthophosphate dikinase regulatory proteins of Arabidopsis possess  a novel, unprecedented Ser/Thr protein kinase primary structure.
  Journal
Plant. J. 53 (2008) 854-63.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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