KEGG   ENZYME: 2.7.4.10Help
Entry
EC 2.7.4.10                 Enzyme                                 

Name
nucleoside-triphosphate---adenylate kinase;
guanosine triphosphate-adenylate kinase;
nucleoside triphosphate-adenosine monophosphate transphosphorylase;
GTP:AMP phosphotransferase;
isozyme 3 of adenylate kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor
BRITE hierarchy
Sysname
nucleoside-triphosphate:AMP phosphotransferase
Reaction(IUBMB)
nucleoside triphosphate + AMP = nucleoside diphosphate + ADP [RN:R00333]
Reaction(KEGG)
Substrate
nucleoside triphosphate [CPD:C00201];
AMP [CPD:C00020]
Product
nucleoside diphosphate [CPD:C00454];
ADP [CPD:C00008]
Comment
Many nucleoside triphosphates can act as donors.
History
EC 2.7.4.10 created 1965
Pathway
Pyrimidine metabolism
Orthology
K00944  
nucleoside-triphosphate--adenylate kinase
Genes
HSA: 
50808(AK3)
PTR: 
464977(AK3)
PPS: 
GGO: 
PON: 
MCC: 
694714(AK3)
MCF: 
MMU: 
56248(Ak3)
RNO: 
26956(Ak3)
CGE: 
HGL: 
TUP: 
CFA: 
AML: 
FCA: 
PTG: 
BTA: 
281613(AK3)
BOM: 
PHD: 
CHX: 
SSC: 
CFR: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
426534(AK3)
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
PSS: 
CMY: 
ACS: 
XLA: 
XTR: 
DRE: 
406404(ak3)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
BFO: 
SPU: 
ISC: 
NVE: 
HMG: 
ZMA: 
TPS: 
NGD: 
SSE: 
 » show all
Taxonomy
Reference
1  [PMID:5423264]
  Authors
Albrecht GJ.
  Title
Purification and properties of nucleoside triphosphate-adenosine monophosphate transphosphorylase from beef heart mitochondria.
  Journal
Biochemistry. 9 (1970) 2462-70.
  Organism
Bos taurus
Reference
2  [PMID:13693071]
  Authors
CHIGA M, ROGERS AE, PLAUT GW.
  Title
Nucleotide transphosphorylases from liver. II. Purification and properties of a 6-oxypurine nucleoside triphosphate-adenosine monophosphate transphosphorylase from swine liver.
  Journal
J. Biol. Chem. 236 (1961) 1800-5.
  Organism
Sus scofa
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9026-74-8

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