| Entry |
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| Name |
isopentenyl phosphate kinase
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor
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| Sysname |
ATP:isopentenyl phosphate phosphotransferase
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| Reaction(IUBMB) |
ATP + isopentenyl phosphate = ADP + isopentenyl diphosphate [RN: R10093]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme is involved in the mevalonate pathway in Archaea [1]. The activity has also been identified in the plant Mentha piperita (peppermint) [2]. It is strictly specific for ATP but can use other phosphate acceptors such as dimethylallyl phosphate, geranyl phosphate, or fosfomycin.
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| Orthology |
| isopentenyl phosphate kinase |
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| Genes |
RRS: | | RCA: | | CAU: | | CAG: | | CHL: | | HAU: | | ATM: | | CAP: | | MJA: | | MFE: | | MVU: | | MFS: | | MIF: | | MIG: | | MMP: | | MMQ: | | MMX: | | MMZ: | | MMD: | | MAE: | | MVN: | | MVO: | | MOK: | | MAC: | | MBA: | | MMA: | | MBU: | | MMH: | | MEV: | | MZH: | | MPY: | | MHZ: | | MTP: | | MCJ: | | MHI: | | MHU: | | MLA: | | MEM: | | MBG: | | MPI: | | MBN: | | MFO: | | MPL: | | MPD: | | MEZ: | | RCI: | | MTH: | | MMG: | | MST: | | MSI: | | MRU: | | MEL: | | MEW: | | MFV: | | MKA: | | AFU: | | APO: | | AVE: | | FPL: | | HAL: | | HSL: | | HMA: | | HHI: | | HWA: | | HWC: | | NPH: | | NMO: | | HLA: | | HUT: | | HMU: | | HTU: | | NMG: | | HVO: | | HME: | | HJE: | | HBO: | | HXA: | | NAT: | | NPE: | | NGE: | | HRU: | | NOU: | | TAC: | | TVO: | | PTO: | | TAR: | | PHO: | | PAB: | | PFU: | | PFI: | | PYN: | | PYA: | | PYS: | | TKO: | | TON: | | TGA: | | TSI: | | TBA: | | THE: | | THA: | | THM: | | ABI: | | ACF: | | MAX: | | APE: | | SMR: | | SHC: | | IHO: | | DKA: | | DMU: | | DFD: | | TAG: | | IAG: | | THG: | | HBU: | | PFM: | | SSO: | | SOL: | | SIS: | | SIA: | | SIM: | | SID: | | SIY: | | SIN: | | SII: | | SIH: | | SIR: | | SIC: | | MSE: | | MCN: | | AHO: | | PAI: | | PIS: | | PCL: | | PAS: | | PYR: | | POG: | | CMA: | | TNE: | | TUZ: | | TTN: | | VDI: | | VMO: | | TPE: | | ASC: | | CLG: | | FFO: | | NMR: | | NIR: | | NKR: | | CSY: | | NGA: | | KCR: | | HAH: | |
» show all
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| Reference |
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| Authors |
Grochowski LL, Xu H, White RH |
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| Title |
Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate. |
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| Journal |
J. Bacteriol. 188 (2006) 3192-8. |
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| Reference |
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| Authors |
Lange BM, Croteau R |
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| Title |
Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: isopentenyl monophosphate kinase catalyzes the terminal enzymatic step. |
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| Journal |
Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 13714-9. |
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| Reference |
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| Authors |
Chen M, Poulter CD |
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| Title |
Characterization of thermophilic archaeal isopentenyl phosphate kinases. |
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| Journal |
Biochemistry. 49 (2010) 207-17. |
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| Reference |
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| Authors |
Mabanglo MF, Schubert HL, Chen M, Hill CP, Poulter CD |
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| Title |
X-ray structures of isopentenyl phosphate kinase. |
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| Journal |
ACS. Chem. Biol. 5 (2010) 517-27. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: |
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