KEGG   ENZYME: 2.7.4.4Help
Entry
EC 2.7.4.4                  Enzyme                                 

Name
nucleoside-phosphate kinase;
NMP-kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor
BRITE hierarchy
Sysname
ATP:nucleoside-phosphate phosphotransferase
Reaction(IUBMB)
ATP + nucleoside phosphate = ADP + nucleoside diphosphate [RN:R00334]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
nucleoside phosphate [CPD:C01329]
Product
ADP [CPD:C00008];
nucleoside diphosphate [CPD:C00454]
Comment
Many nucleotides can act as acceptors; other nucleoside triphosphates can act instead of ATP.
History
EC 2.7.4.4 created 1961
Reference
1  [PMID:13363863]
  Authors
AYENGAR P, GIBSON DM, SANADI DR.
  Title
Transphosphorylations between nucleoside phosphates.
  Journal
Biochim. Biophys. Acta. 21 (1956) 86-91.
Reference
2  [PMID:14401179]
  Authors
HEPPEL LA, STROMINGER JL, MAXWELL ES.
  Title
Nucleoside monophosphate kinases. II. Transphosphorylation betweeen adenosine monophosphate and nucleoside triphosphates.
  Journal
Biochim. Biophys. Acta. 32 (1959) 422-30.
Reference
3  [PMID:14392176]
  Authors
LIEBERMAN I, KORNBERG A, SIMMS ES.
  Title
Enzymatic synthesis of nucleoside diphosphates and triphosphates.
  Journal
J. Biol. Chem. 215 (1955) 429-40.
Reference
4
  Authors
Noda, L.
  Title
Nucleoside triphosphate-nucleoside monophosphokinases.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 6, Academic Press, New York, 1962, p. 139-149.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9026-50-0

DBGET integrated database retrieval system