KEGG   ENZYME: 2.7.7.34Help
Entry
EC 2.7.7.34                 Enzyme                                 

Name
glucose-1-phosphate guanylyltransferase;
GDP glucose pyrophosphorylase;
guanosine diphosphoglucose pyrophosphorylase
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
BRITE hierarchy
Sysname
GTP:alpha-D-glucose-1-phosphate guanylyltransferase
Reaction(IUBMB)
GTP + alpha-D-glucose 1-phosphate = diphosphate + GDP-glucose [RN:R00954]
Reaction(KEGG)
Substrate
GTP [CPD:C00044];
alpha-D-glucose 1-phosphate [CPD:C00103]
Product
diphosphate [CPD:C00013];
GDP-glucose [CPD:C00394]
Comment
Also acts, more slowly, on D-mannose 1-phosphate.
History
EC 2.7.7.34 created 1972
Pathway
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Metabolic pathways
Reference
1  [PMID:6034677]
  Authors
Danishefsky I, Heritier-Watkins O.
  Title
Nucleoside diphosphate glucose pyrophosphorylases in mast cell tumors.
  Journal
Biochim. Biophys. Acta. 139 (1967) 349-57.
  Organism
Eremothecium ashbyii, mammalian
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9033-13-0

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