KEGG   ENZYME: 2.7.7.47Help
Entry
EC 2.7.7.47                 Enzyme                                 

Name
streptomycin 3''-adenylyltransferase;
streptomycin adenylate synthetase;
streptomycin adenyltransferase;
streptomycin adenylylase;
streptomycin adenylyltransferase;
streptomycin-spectinomycin adenylyltransferase;
AAD (3'');
aminoglycoside 3''-adenylyltransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
BRITE hierarchy
Sysname
ATP:streptomycin 3''-adenylyltransferase
Reaction(IUBMB)
ATP + streptomycin = diphosphate + 3''-adenylylstreptomycin [RN:R02226]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
streptomycin [CPD:C00413]
Product
diphosphate [CPD:C00013];
3''-adenylylstreptomycin [CPD:C03462]
Comment
Also acts on spectinomycin.
History
EC 2.7.7.47 created 1976
Orthology
K00984  
streptomycin 3"-adenylyltransferase
Genes
ECV: 
ECM: 
EUM: 
STY: 
STY1857(aadA)
STT: 
t1142(aadA)
STM: 
STM1264(aadA)
SEM: 
SETU: 
SPT: 
SPA1582(aadA)
SEK: 
SPQ: 
SEI: 
SPC_2479(aadA)
SEC: 
SC032(aadA2) SC051(aadA2) SC053(aadA2) SC1275(aadA)
SEH: 
SEE: 
SEW: 
SEA: 
SEG: 
SG1860(aadA)
SET: 
SEN1788(aadA)
SSN: 
SSON_3896(aadA)
KPN: 
KPH: 
KPG: 
KPC: 
KPNE: 
KPNU: 
KOE: 
PSU: 
PMY: 
PSA: 
ACB: 
ABM: 
ABY: 
ABC: 
ABN: 
ABB: 
LPP: 
LPC: 
ASA: 
CTI: 
BUR: 
BCM: 
BCJ: 
BAM: 
BAC: 
BPA: 
BPP1010(aadA4)
BBR: 
BB1224(aadA4)
AXY: 
VAP: 
MMS: 
mma_1582(aadA4)
NMU: 
DDS: 
MXA: 
SME: 
SMD: 
PDE: 
GWC: 
EAT: 
PJD: 
GYM: 
LPJ: 
LRH: 
LRL: 
EFA: 
THL: 
CBI: 
CKL: 
CKR: 
AOE: 
CCE: 
CLE: 
CPY: 
DSY: 
DHD: 
SCO: 
SCO4355(SCD19.10)
BCV: 
IVA: 
MPH: 
SVI: 
RCA: 
DIN: 
 » show all
Taxonomy
Reference
1  [PMID:4887506]
  Authors
Harwood JH, Smith DH.
  Title
Resistance factor-mediated streptomycin resistance.
  Journal
J. Bacteriol. 97 (1969) 1262-71.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
52660-23-8

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