KEGG ENZYME: 2.7.8.15

ENZYME: 2.7.8.15

Entry

EC 2.7.8.15 Enzyme

Name

UDP-N-acetylglucosamine---dolichyl-phosphate N-acetylglucosaminephosphotransferase;
UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase;
UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase;
UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase;
uridine diphosphoacetylglucosamine-dolichyl phosphate acetylglucosamine-1-phosphotransferase;
chitobiosylpyrophosphoryldolichol synthase;
dolichol phosphate N-acetylglucosamine-1-phosphotransferase;
UDP-acetylglucosamine-dolichol phosphate acetylglucosamine phosphotransferase;
UDP-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphotransferase

Class

Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups

Sysname

UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase

Reaction(IUBMB)

UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol [RN:R01007 R05969]

Reaction(KEGG)

R01007 R05969(G)

Substrate

UDP-N-acetyl-D-glucosamine [CPD:C00043];
dolichyl phosphate [CPD:C00110]

Product

UMP [CPD:C00105];
N-acetyl-D-glucosaminyl-diphosphodolichol [CPD:C04500]

Pathway

ec00510	N-Glycan biosynthesis
ec01100	Metabolic pathways

Orthology

K01001

UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

Genes

HSA:	1798(DPAGT1)
PTR:	451602(DPAGT1)
PPS:	100993250(DPAGT1)
GGO:	101136067(DPAGT1)
PON:	100447980(DPAGT1)
MCC:	703538(DPAGT1)
MMU:	13478(Dpagt1)
RNO:	300668(Dpagt1)
CFA:	489371(DPAGT1)
AML:	100484813
FCA:	101095368(DPAGT1)
BTA:	537812(DPAGT1)
SSC:	100517773
ECB:	100063303
MDO:	100031278
SHR:	100922199(DPAGT1)
OAA:	100086347
GGA:	419699(DPAGT1)
MGP:	100541475
TGU:	100222476(DPAGT1)
ACS:	100563767
XTR:	100487779
DRE:	566539(dpagt1)
TRU:	101068851
OLA:	101160503
BFO:	BRAFLDRAFT_275916
CIN:	100185972
SPU:	590324
DME:	Dmel_CG5287
DPO:	Dpse_GA18787
DAN:	Dana_GF14223
DER:	Dere_GG23818
DPE:	Dper_GL24744
DSE:	Dsec_GM10202
DSI:	Dsim_GD23869
DWI:	Dwil_GK23958
DYA:	Dyak_GE18620
DGR:	Dgri_GH11394
DMO:	Dmoj_GI18098
DVI:	Dvir_GJ16886
AGA:	AgaP_AGAP008131
AAG:	AaeL_AAEL005705
CQU:	CpipJ_CPIJ000918
AME:	552327
NVI:	100121145(NV14606)
TCA:	656424
API:	100165754
PHU:	Phum_PHUM609410
CEL:	CELE_Y60A3A.14
CBR:	CBG24468
BMY:	Bm1_52335
SMM:	Smp_051360.1
NVE:	NEMVE_v1g247774
HMG:	100200383
TAD:	TRIADDRAFT_18613
AQU:	100632537
ATH:	AT2G41490(GPT) AT3G57220
ALY:	ARALYDRAFT_483226 ARALYDRAFT_907180
GMX:	100789475 100801463
CSV:	101223589
RCU:	RCOM_0255510
POP:	POPTR_1103021 POPTR_417910
VVI:	100252210
OSA:	4344180
DOSA:	Os07t0661100-01(Os07g0661100)
BDI:	100824570
SBI:	SORBI_02g041960(SORBIDRAFT_02g041960)
ZMA:	100274497 100281216
SMO:	SELMODRAFT_171816 SELMODRAFT_77123
PPP:	PHYPADRAFT_171226
CRE:	CHLREDRAFT_139119
VCN:	VOLCADRAFT_91192
OLU:	OSTLU_17763
OTA:	Ot13g00590
CME:	CMQ042C
SCE:	YBR243C(ALG7)
AGO:	AGOS_AFL037W
ERC:	Ecym_2259
KLA:	KLLA0F06776g
LTH:	KLTH0H05632g
PPA:	PAS_chr2-1_0727
VPO:	Kpol_534p26
ZRO:	ZYRO0G21714g
CGR:	CAGL0C01727g
NCS:	NCAS_0H01210(NCAS0H01210)
NDI:	NDAI_0F02080(NDAI0F02080)
TPF:	TPHA_0N01080(TPHA0N01080)
TBL:	TBLA_0B04660(TBLA0B04660)
TDL:	TDEL_0B03960(TDEL0B03960)
KAF:	KAFR_0G03560(KAFR0G03560)
DHA:	DEHA2C10142g
PIC:	PICST_36364(ALG7)
PGU:	PGUG_03727
LEL:	LELG_01930
CAL:	CaO19.2187(ALG7) CaO19.9733(ALG7)
CTP:	CTRG_01670
CDU:	CD36_22170
COT:	CORT_0B05450
YLI:	YALI0B16588g
CLU:	CLUG_05441
NCR:	NCU10762
TTT:	THITE_2075857
MTM:	MYCTH_2299371
MGR:	MGG_01559
FGR:	FG09584.1
NHE:	NECHADRAFT_91141
VAL:	VDBG_00948
SSL:	SS1G_07730
BFU:	BC1G_15896
ANI:	AN5888.2
NFI:	NFIA_086520
AFM:	AFUA_2G11240
AOR:	AOR_1_1638014(AO090026000526)
ANG:	ANI_1_2396024(An02g03240)
AFV:	AFLA_134070
ACT:	ACLA_070210
PCS:	Pc15g00540
CIM:	CIMG_08206
CPW:	CPC735_022230
PBL:	PAAG_03295
ABE:	ARB_01331
TVE:	TRV_07373
PNO:	SNOG_13671
PTE:	PTT_09556
ZTR:	MYCGRDRAFT_72420(Mg77997)
TML:	GSTUM_00010445001
SPO:	SPBC15D4.04(gpt2)
CNE:	CNK00270
CNB:	CNBK3150
CGI:	CGB_K4240W
LBC:	LACBIDRAFT_309240(ALG7)
MPR:	MPER_04338
CCI:	CC1G_07121
SCM:	SCHCODRAFT_53029
UMA:	UM03679.1
MGL:	MGL_3398
PGR:	PGTG_13425
MBR:	MONBRDRAFT_18170
NGR:	NAEGRDRAFT_31656
DPP:	DICPUDRAFT_158539
EHI:	EHI_062840(142.t00005)
EDI:	EDI_044380
PFA:	PFC0935c
PYO:	PY00432
PBE:	PB000880.00.0
PKN:	PKH_081940
PVX:	PVX_095175
PCY:	PCYB_082860
TAN:	TA18965
TPV:	TP01_0118
BBO:	BBOV_IV000950(21.m03089)
CPV:	cgd5_2240
CHO:	Chro.50156
TGO:	TGME49_044520
TET:	TTHERM_00070990
PTM:	GSPATT00029124001
TBR:	Tb11.01.2220
TCR:	503823.104 510283.140
LMA:	LMJF_36_4180
LIF:	LINJ_36_4390
LDO:	LDBPK_364390
LMI:	LMXM_36_4180
LBZ:	LBRM_35_4430
GLA:	GL50803_15889
TVA:	TVAG_308000
PTI:	PHATRDRAFT_9724
TPS:	THAPSDRAFT_14875
PIF:	PITG_17022
MJA:	MJ_1113
MFE:	Mefer_0304
MVU:	Metvu_1370
MFS:	MFS40622_0053
MIF:	Metin_0640
MIG:	Metig_1796
MMP:	MMP1423
MMQ:	MmarC5_0155
MMX:	MmarC6_1250
MMZ:	MmarC7_0668
MMD:	GYY_07950
MAE:	Maeo_1408
MVN:	Mevan_0734
MVO:	Mvol_1039
MOK:	Metok_0790
MMA:	MM_2096
MMAZ:	MmTuc01_2159
MBU:	Mbur_0124
MPY:	Mpsy_0714
MTP:	Mthe_0944
MTH:	MTH590
MMG:	MTBMA_c09700
MST:	Msp_0080
MSI:	Msm_0066
MRU:	mru_0964
MFV:	Mfer_0609
FPL:	Ferp_1927
PHO:	PH0348
PAB:	PAB1288
PFU:	PF0394
PFI:	PFC_01055
PYN:	PNA2_0960
PYA:	PYCH_13870
PYS:	Py04_0658
TKO:	TK2254
TON:	TON_1365
TSI:	TSIB_1273
TBA:	TERMP_00953
THE:	GQS_08665
THM:	CL1_1341
ABI:	Aboo_0242
ACF:	AciM339_0813
SMR:	Smar_0181
SHC:	Shell_0644
IHO:	Igni_0775
DKA:	DKAM_0677
DMU:	Desmu_0391
DFD:	Desfe_0833
TAG:	Tagg_0335
IAG:	Igag_0250
THG:	TCELL_1346
HBU:	Hbut_1432
PFM:	Pyrfu_1701
SSO:	SSO0060(gnptA)
SOL:	Ssol_1041
STO:	ST2057
SAI:	Saci_0093
SACN:	SacN8_00445
SACR:	SacRon12I_00445
SIS:	LS215_2224
SIA:	M1425_2059
SIM:	M1627_2139
SID:	M164_2066
SIY:	YG5714_2185
SIN:	YN1551_0734
SII:	LD85_2326
SIH:	SiH_2005
SIR:	SiRe_1932
SIC:	SiL_1912
MSE:	Msed_2134
MCN:	Mcup_0155
AHO:	Ahos_0650
PAI:	PAE3488
PIS:	Pisl_0784
PCL:	Pcal_1170
PAS:	Pars_1969
PYR:	P186_0644
POG:	Pogu_0153
TNE:	Tneu_0862
CMA:	Cmaq_0977
TUZ:	TUZN_0372
TTN:	TTX_0722(gpt)
VDI:	Vdis_2497
VMO:	VMUT_0773
TPE:	Tpen_0412
ASC:	ASAC_0068
CLG:	Calag_1078
FFO:	FFONT_0416
NMR:	Nmar_0244
NIR:	NSED_01130
NKR:	NKOR_01070
CSY:	CENSYa_1721
NGA:	Ngar_c07320
NEQ:	NEQ061
KCR:	Kcr_1444 Kcr_1445

» show all

Reference

1 [PMID:6215245]

Authors

Sharma CB, Lehle L, Tanner W.

Title

Solubilization and characterization of the initial enzymes of the dolichol pathway from yeast.

Journal

Eur. J. Biochem. 126 (1982) 319-25.

Organism

Saccharomyces cerevisiae [GN:sce]

Reference

2 [PMID:6447695]

Authors

Villemez CL, Carlo PL.

Title

Properties of a soluble polyprenyl phosphate. UDP-D-N-acetylglucosamine N-acetylglucosamine-1-phosphate transferase.

Journal

J. Biol. Chem. 255 (1980) 8174-8.

Organism

Acanthamoeba castellanii

Other DBs

ExplorEnz - The Enzyme Database:

2.7.8.15

IUBMB Enzyme Nomenclature:

2.7.8.15

ExPASy - ENZYME nomenclature database:

2.7.8.15

BRENDA, the Enzyme Database:

2.7.8.15

CAS:

70431-08-2

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Ontology (4)   
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Gene (517)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (272)   
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   KEGG EGENES (142)   
   KEGG MGENES (85)   
Protein sequence (124)   
   UniProt (69)   
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