KEGG   ENZYME: 2.7.8.24Help
Entry
EC 2.7.8.24                 Enzyme                                 
Name phosphatidylcholine synthase;
CDP-diglyceride-choline O-phosphatidyltransferase
Class Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
BRITE hierarchy
Sysname CDP-diacylglycerol:choline O-phosphatidyltransferase
Reaction(IUBMB) CDP-diacylglycerol + choline = CMP + phosphatidylcholine [RN:R05794]
Reaction(KEGG) R05794
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Substrate CDP-diacylglycerol [CPD:C00269];
choline [CPD:C00114]
Product CMP [CPD:C00055];
phosphatidylcholine [CPD:C00157]
Comment Requires divalent cations, with Mn2+ being more effective than Mg2+.
Pathway ec00564  Glycerophospholipid metabolism
Orthology K01004  phosphatidylcholine synthase
Genes PAE: PA3857(pcs)
PAU: PA14_14110(pcs)
PAP: PSPA7_1254
PAG: PLES_11171(pcs)
PST: PSPTO_1000
PSB: Psyr_0866
PSP: PSPPH_0901
PFL: PFL_4055
PFO: Pfl01_2093
PFS: PFLU2780
PMY: Pmen_3554
LPN: lpg1584
LPF: lpl1441(lidK)
LPP: lpp1542(lidK)
LPC: LPC_1009(lidK)
LPA: lpa_02301(lidK)
LLO: LLO_1806(lidK)
FTU: FTT_1563(pcs)
FTF: FTF1563(pcs)
FTW: FTW_0364
FTL: FTL_0545
FTH: FTH_0547(pcs)
FTA: FTA_0578
FTM: FTM_0336(pcs)
FTN: FTN_1471(pcs)
FPH: Fphi_1204
DRT: Dret_1145
MLO: mll0506
MES: Meso_1695
PLA: Plav_1484
SME: SMc00247(pcs)
SMD: Smed_1420
ATU: Atu1793(pcs)
ARA: Arad_2343(pcs)
AVI: Avi_2165(pcs)
RET: RHE_CH02079(pcs)
REC: RHECIAT_CH0002129(pcs)
RLE: RL2370(pcs)
RLT: Rleg2_1714
RLG: Rleg_1898
RHI: NGR_c14490(pcs)
LAS: CLIBASIA_03680
BME: BMEII0695
BMI: BMEA_B0545
BMF: BAB2_0668
BMB: BruAb2_0652(pcs)
BMC: BAbS19_II06250
BMS: BRA0572(pcs)
BMT: BSUIS_B0568
BOV: BOV_A0538
BCS: BCAN_B0572
BMR: BMI_II566(pcs)
OAN: Oant_3634
BJA: bll4585(pcs)
BRA: BRADO3781
BBT: BBta_4148
RPA: RPA2672
RPB: RPB_2842
RPC: RPC_2618
RPD: RPD_2630
RPE: RPE_2798
RPT: Rpal_2947
NWI: Nwi_1506
NHA: Nham_2046
OCA: OCAR_6201
BHE: BH08530(pcsA)
BQU: BQ06040(pcsA)
BBK: BARBAKC583_0817(pcs)
BTR: Btr_1173
BGR: Bgr_10750(pcsA)
SNO: Snov_1703
SIL: SPO3131(pcs)
SIT: TM1040_2382
RSP: RSP_0565
RSH: Rsph17029_2217
RSQ: Rsph17025_0497
RSK: RSKD131_1903
RCP: RCAP_rcc03206(pcs)
JAN: Jann_1029
RDE: RD1_2077(pcs)
PDE: Pden_0811
RCE: RC1_1051(pcs)
AZL: AZL_005000(pcs)
KFL: Kfla_2262
GOB: Gobs_4045
AHE: Arch_0709
RXY: Rxyl_0272
BBU: BB0249
BBZ: BbuZS7_0254
BGA: BG0251
BAF: BAPKO_0258
BTU: BT0249
BHR: BH0249
BDU: BDU_250
BRE: BRE_249
SRU: SRU_0340
SRM: SRM_00419(pssA)
RBA: RB4506
TRA: Trad_0527
Taxonomy
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:10391951]
de Rudder KE, Sohlenkamp C, Geiger O.
Plant-exuded choline is used for rhizobial membrane lipid
biosynthesis by phosphatidylcholine synthase.
J. Biol. Chem. 274 (1999) 20011-6.
Sinorhizobium meliloti [GN:sme]
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:10858449]
Sohlenkamp C, de Rudder KE, Rohrs V, Lopez-Lara IM, Geiger O.
Cloning and characterization of the gene for phosphatidylcholine
synthase.
J. Biol. Chem. 275 (2000) 18919-25.
Sinorhizobium meliloti [GN:sme]
Other DBs ExplorEnz - The Enzyme Database: 2.7.8.24
IUBMB Enzyme Nomenclature: 2.7.8.24
ExPASy - ENZYME nomenclature database: 2.7.8.24
BRENDA, the Enzyme Database: 2.7.8.24
CAS: 243666-86-6
DBGET integrated database retrieval system