KEGG   ENZYME: 2.7.8.3Help
Entry
EC 2.7.8.3                  Enzyme                                 

Name
ceramide cholinephosphotransferase;
phosphorylcholine-ceramide transferase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
BRITE hierarchy
Sysname
CDP-choline:N-acylsphingosine cholinephosphotransferase
Reaction(IUBMB)
CDP-choline + a ceramide = CMP + sphingomyelin [RN:R01891]
Reaction(KEGG)
Substrate
CDP-choline [CPD:C00307];
ceramide [CPD:C00195]
Product
CMP [CPD:C00055];
sphingomyelin [CPD:C00550]
History
EC 2.7.8.3 created 1965
Pathway
Sphingolipid metabolism
Metabolic pathways
Reference
1
  Authors
Kennedy, E.P.
  Title
Phosphorylcholine-glyceride transferase.
  Journal
Methods Enzymol. 5 (1962) 484-486.
Reference
2  [PMID:13610834]
  Authors
SRIBNEY M, KENNEDY EP.
  Title
The enzymatic synthesis of sphingomyelin.
  Journal
J. Biol. Chem. 233 (1958) 1315-22.
  Organism
Gallus gallus [GN:gga]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9026-14-6

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