KEGG   ENZYME: 2.7.8.38Help
Entry
EC 2.7.8.38                 Enzyme                                 

Name
archaetidylserine synthase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
BRITE hierarchy
Sysname
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol:L-serine 2,3-bis-(O-geranylgeranyl)-sn-glycerol phosphotransferase
Reaction(IUBMB)
(1) CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol + L-serine = CMP + 2,3-bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine [RN:R10255];
(2) CDP-2,3-bis-(O-phytanyl)-sn-glycerol + L-serine = CMP + 2,3-bis-(O-phytanyl)-sn-glycero-1-phospho-L-serine [RN:R10441]
Reaction(KEGG)
Substrate
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol;
L-serine [CPD:C00065];
CDP-2,3-bis-(O-phytanyl)-sn-glycerol [CPD:C20627]
Product
CMP [CPD:C00055];
2,3-bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine;
2,3-bis-(O-phytanyl)-sn-glycero-1-phospho-L-serine [CPD:C20628]
Comment
Requires Mn2+. Isolated from the archaeon Methanothermobacter thermautotrophicus.
History
EC 2.7.8.38 created 2013, modified 2013
Pathway
Glycerophospholipid metabolism
Orthology
K19665  
archaetidylserine synthase
Genes
MTH: 
MMG: 
METC: 
MST: 
MSI: 
MRU: 
mru_1834(pssA)
MEB: 
MEL: 
MEW: 
METH: 
MFC: 
BRM9_2090(pssA)
MFI: 
 » show all
Taxonomy
Reference
1  [PMID:12562787]
  Authors
Morii H, Koga Y
  Title
CDP-2,3-Di-O-geranylgeranyl-sn-glycerol:L-serine O-archaetidyltransferase (archaetidylserine synthase) in the methanogenic archaeon Methanothermobacter thermautotrophicus.
  Journal
J. Bacteriol. 185 (2003) 1181-9.
  Sequence
[mth:MTH_1027]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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