KEGG   ENZYME: 2.7.8.39Help
Entry
EC 2.7.8.39                 Enzyme                                 

Name
archaetidylinositol phosphate synthase;
AIP synthase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
BRITE hierarchy
Sysname
CDP-2,3-bis-(O-phytanyl)-sn-glycerol:1L-myo-inositol 1-phosphate 1-sn-archaetidyltransferase
Reaction(IUBMB)
CDP-2,3-bis-(O-phytanyl)-sn-glycerol + 1L-myo-inositol 1-phosphate = CMP + 1-archaetidyl-1D-myo-inositol 3-phosphate [RN:R10464]
Reaction(KEGG)
Substrate
CDP-2,3-bis-(O-phytanyl)-sn-glycerol [CPD:C20627];
1L-myo-inositol 1-phosphate [CPD:C04006]
Product
CMP [CPD:C00055];
1-archaetidyl-1D-myo-inositol 3-phosphate [CPD:C20642]
Comment
Requires Mg2+ or Mn2+ for activity. The enzyme is involved in biosynthesis of archaetidyl-myo-inositol, a compound essential for glycolipid biosynthesis in archaea.
History
EC 2.7.8.39 created 2013
Orthology
K17884  archaetidylinositol phosphate synthase
Genes
VNI: VIBNI_A3472
LSH: CAB17_02425
DSF: UWK_00876
MAC: MA_0525
MBA: Mbar_A1498
MBY: MSBRM_0465
MBW: MSBRW_3231
MBAR: MSBR2_1917
MBAK: MSBR3_1948
MMA: MM_1685
MMAC: MSMAC_1447
METM: MSMTP_2914
MTHE: MSTHC_1224
MTHR: MSTHT_2060
MHOR: MSHOH_3692
MMET: MCMEM_0893
MMH: Mmah_1332
MPY: Mpsy_0420
MCJ: MCON_0773
MHI: Mhar_0485
MBG: BN140_0481(pgsA3) BN140_1190(pgsA5)
MEMA: MMAB1_0596(pgsA) MMAB1_1510
MPD: MCP_2312
MEZ: Mtc_1266
MTH: MTH_1691
METC: MTCT_1543
MWO: MWSIV6_0228(aipS)
METE: tca_01637(pgsA)
MST: Msp_0095
MSI: Msm_0613
MRU: mru_0503(pgsA)
MEB: Abm4_0270
MMIL: sm9_0362(pgsA)
MEYE: TL18_01585
MOL: YLM1_0176
METH: MBMB1_1397
MFC: BRM9_0633(pgsA1)
MCUB: MCBB_1640
MFV: Mfer_0753
AFU: AF_1744
FPL: Ferp_2483
GAC: GACE_1907
GAH: GAH_00749
HAL: VNG_1030G(pgsA)
HSL: OE_2503R(pgsA2)
HHB: Hhub_2229(pgsA2)
HALH: HTSR_0913(pgsA)
HHSR: HSR6_0927(pgsA2)
HSU: HLASF_1550(pgsA)
HSF: HLASA_1537(pgsA)
HMA: rrnAC0532(pgsA)
HHI: HAH_1110(pgsA)
NPH: NP_2144A(agsA)
NMO: Nmlp_3182(pgsA2)
HUT: Huta_0365
HTI: HTIA_0540
HMU: Hmuk_2373
HWA: HQ_3362A(agsA)
HWC: Hqrw_3886(agsA)
HVO: HVO_1297(pgsA)
HME: HFX_1362(pgsA)
HLA: Hlac_1342
HTU: Htur_1902
NMG: Nmag_0605
NAT: NJ7G_0772
SALI: L593_10870
TAC: Ta0569
TVO: TVG0612669(TVG0612669)
PTO: PTO1167
FAI: FAD_0601
CDIV: CPM_0358
MARC: AR505_1783
PHO: PH0460(PH0460)
PAB: PAB1041(pgsA-like)
PFU: PF0462
PFI: PFC_01425
PYN: PNA2_1091
PYS: Py04_0642
TKO: TK0059
TON: TON_1168
TGA: TGAM_1165
TSI: TSIB_1086
THE: GQS_09735
THM: CL1_1535
TLT: OCC_07616
THS: TES1_1265
TNU: BD01_1131
TEU: TEU_11545
PPAC: PAP_07230
ABI: Aboo_1228
ACJ: ACAM_0959
SMR: Smar_1186
IHO: Igni_0052
IIS: EYM_04555
DKA: DKAM_0985
TAG: Tagg_0092
IAG: Igag_1942
HBU: Hbut_1537
SSO: SSO0556(pgsA)
SOL: Ssol_1624
SSOA: SULA_1652
SSOL: SULB_1653
SSOF: SULC_1651
STO: STK_14300
SAI: Saci_1541
SID: M164_1569
SII: LD85_1780
SIH: SiH_1538
SIR: SiRe_1447
SIC: SiL_1449
MSE: Msed_1911
MCN: Mcup_0374
AHO: Ahos_1182
PAI: PAE2176
PIS: Pisl_0818
PCL: Pcal_1089
PAS: Pars_0800
PYR: P186_0415
POG: Pogu_1532
TNE: Tneu_1363
CMA: Cmaq_1924
TUZ: TUZN_1180
TTN: TTX_0165(pgsA)
VDI: Vdis_1838
VMO: VMUT_0277
TPE: Tpen_0218
ASC: ASAC_0559
NMR: Nmar_0924
NCT: NMSP_0918
NGA: Ngar_c16520(pgsA)
NVN: NVIE_005560(pgsA)
NEV: NTE_01924
TAA: NMY3_02475(pgsA1)
NCV: NCAV_0754
NBV: T478_0797
NDV: NDEV_1139(pgsA)
KCR: Kcr_0118
BARC: AOA65_0541
BARB: AOA66_1239
 » show all
Taxonomy
Reference
1  [PMID:19740749]
  Authors
Morii H, Kiyonari S, Ishino Y, Koga Y
  Title
A novel biosynthetic pathway of archaetidyl-myo-inositol via archaetidyl-myo-inositol phosphate from CDP-archaeol and D-glucose 6-phosphate in methanoarchaeon Methanothermobacter thermautotrophicus cells.
  Journal
J. Biol. Chem. 284 (2009) 30766-74.
  Sequence
[mth:MTH_1691]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.39
IUBMB Enzyme Nomenclature: 2.7.8.39
ExPASy - ENZYME nomenclature database: 2.7.8.39
BRENDA, the Enzyme Database: 2.7.8.39

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