KEGG   ENZYME: 2.7.8.40Help
Entry
EC 2.7.8.40                 Enzyme                                 

Name
UDP-N-acetylgalactosamine-undecaprenyl-phosphate N-acetylgalactosaminephosphotransferase;
WecP;
UDP-GalNAc:polyprenol-P GalNAc-1-P transferase;
UDP-GalNAc:undecaprenyl-phosphate GalNAc-1-phosphate transferase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
BRITE hierarchy
Sysname
UDP-N-acetyl-alpha-D-galactosamine:ditrans,octacis-undecaprenyl phosphate N-acetyl-D-galactosaminephosphotransferase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol [RN:R10465]
Reaction(KEGG)
Substrate
UDP-N-acetyl-alpha-D-galactosamine [CPD:C00203];
ditrans,octacis-undecaprenyl phosphate [CPD:C17556]
Product
UMP [CPD:C00105];
N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C20620]
Comment
The enzyme catalyses a step in the assembly of the repeating-unit of the O-antigen of the Gram-negative bacterium Aeromonas hydrophila AH-3. The enzyme shows no activity with UDP-N-acetyl-alpha-D-glucosamine (cf. EC 2.7.8.33, UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase).
History
EC 2.7.8.40 created 2013
Reference
1  [PMID:21335454]
  Authors
Merino S, Jimenez N, Molero R, Bouamama L, Regue M, Tomas JM
  Title
A UDP-HexNAc:polyprenol-P GalNAc-1-P transferase (WecP) representing a new subgroup of the enzyme family.
  Journal
J. Bacteriol. 193 (2011) 1943-52.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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